| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GSK3B | CLOCK | Ser427 | ALERFDHsPTPSASS | phosphorylation down-regulates quantity by destabilization | 19946213 | SIGNOR-276270 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GSK3B | phosphorylation up-regulates → | CLOCK PSer427 | phosphorylation down-regulates ⊣ | CLOCK | 19946213 | SIGNOR-276270 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| GSK3B | phosphorylation![]() down-regulates quantity by destabilization | CLOCK | SIGNOR-276270 |