| Name | PDPK1 |
| ID | O15530 |
| Role | kinase |
| Enzymatic Domains |
Protein kinase 82-342 PROSITE-ProRule
PH 459-550 |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PDPK1 | RPS6K | Ser221 | DHEKKAYsFCGTVEY | phosphorylation up-regulates activity | 10480933 | SIGNOR-252763 |
| PDPK1 | RPS6KB1 | Thr252 | HDGTVTHtFCGTIEY | phosphorylation up-regulates | 19864428 | SIGNOR-188907 |
| PDPK1 | RPS6KA3 | Ser227 | DHEKKAYsFCGTVEY | phosphorylation up-regulates | 10480933 | SIGNOR-70612 |
| PDPK1 | PRKCE | Thr566 | LNGVTTTtFCGTPDY | phosphorylation up-regulates | 11964154 | SIGNOR-117320 |
| PDPK1 | RPS6KB2 | Thr228 | HEGAVTHtFCGTIEY | phosphorylation up-regulates activity | 11733037 | SIGNOR-250273 |
| PDPK1 | PDPK1 | Ser241 | SKQARANsFVGTAQY | phosphorylation up-regulates activity | 11481331 | SIGNOR-250268 |
| PDPK1 | PRKCH | – | phosphorylation up-regulates activity | 12223477 | SIGNOR-280062 | |
| PDPK1 | RAF1 | – | phosphorylation up-regulates activity | 29575487 | SIGNOR-280063 | |
| PDPK1 | AKT2 | Ser474 | RTHFPQFsYSASIRE | phosphorylation up-regulates activity | 15743829 | SIGNOR-134481 |
| PDPK1 | AKT1 | Thr308 | KDGATMKtFCGTPEY | phosphorylation up-regulates | 12167717 | SIGNOR-91354 |
| PDPK1 | SGK2 | Ser416 | SSAFLGFsYAPEDDD | phosphorylation up-regulates activity | 10548550 | SIGNOR-250376 |
| PDPK1 | RPS6KA1 | Ser221 | DHEKKAYsFCGTVEY | phosphorylation up-regulates activity | 10480933 | SIGNOR-250270 |
| PDPK1 | AKT | – | phosphorylation up-regulates | 21798082 | SIGNOR-244396 | |
| PDPK1 | AKT1 | Thr308 | KDGATMKtFCGTPEY | phosphorylation up-regulates | 10226025 | SIGNOR-67363 |
| PDPK1 | PKN2 | Thr816 | GYGDRTStFCGTPEF | phosphorylation up-regulates | 10753910 | SIGNOR-76710 |
| PDPK1 | AKT1 | Thr308 | KDGATMKtFCGTPEY | phosphorylation up-regulates activity | 19951971 | SIGNOR-249629 |
| PDPK1 | PRKCQ | – | phosphorylation up-regulates | 15802604 | SIGNOR-134869 | |
| PDPK1 | PLK1 | – | phosphorylation up-regulates activity | 23887393 | SIGNOR-243519 | |
| PDPK1 | SGK3 | – | phosphorylation up-regulates | 15209375 | SIGNOR-126236 | |
| PDPK1 | SGK3 | Ser486 | DDAFVGFsYAPPSED | phosphorylation up-regulates activity | 10548550 | SIGNOR-250278 |
| PDPK1 | AKT | Thr308 | KDGATMKtFCGTPEY | phosphorylation up-regulates activity | 9512493 | SIGNOR-244480 |
| PDPK1 | MAP2K1 | Ser222 | LIDSMANsFVGTRSY | phosphorylation up-regulates activity | 15175348 | SIGNOR-236633 |
| PDPK1 | SGK2 | – | phosphorylation up-regulates | 15209375 | SIGNOR-126177 | |
| PDPK1 | ITGB3 | Thr779 | LYKEATStFTNITYR | phosphorylation down-regulates activity | 10896934 | SIGNOR-250266 |
| PDPK1 | SGK1 | Thr256 | EHNSTTStFCGTPEY | phosphorylation up-regulates | 15209375 | SIGNOR-236637 |
| PDPK1 | AKT1 | Thr308 | KDGATMKtFCGTPEY | phosphorylation up-regulates | 12808134 | SIGNOR-252611 |
| PDPK1 | SGK1 | Ser422 | AEAFLGFsYAPPTDS | phosphorylation up-regulates activity | 10191262 | SIGNOR-250274 |
| PDPK1 | AKT3 | Thr305 | TDAATMKtFCGTPEY | phosphorylation up-regulates | 9512493 | SIGNOR-55937 |
| PDPK1 | AKT | Thr308 | KDGATMKtFCGTPEY | phosphorylation up-regulates activity | 15718470 | SIGNOR-243203 |
| PDPK1 | AKT | Thr308 | KDGATMKtFCGTPEY | phosphorylation up-regulates activity | 10226025 | SIGNOR-244421 |
| PDPK1 | SGK1 | Thr256 | EHNSTTStFCGTPEY | phosphorylation up-regulates activity | 10191262 | SIGNOR-250275 |
| PDPK1 | PDPK1 | Ser396 | SSSSSSHsLSASDTG | phosphorylation unknown | 10455013 | SIGNOR-236764 |
| PDPK1 | PKN1 | Thr774 | GYGDRTStFCGTPEF | phosphorylation up-regulates | 10753910 | SIGNOR-76640 |
| PDPK1 | MAP2K2 | Ser226 | LIDSMANsFVGTRSY | phosphorylation up-regulates | 15175348 | SIGNOR-125176 |
| PDPK1 | PDPK1 | Ser25 | VVLCSCPsPSMVRTQ | phosphorylation unknown | 10455013 | SIGNOR-236777 |
| PDPK1 | PDPK1 | Ser393 | MQVSSSSsSHSLSAS | phosphorylation unknown | 10455013 | SIGNOR-235782 |
| PDPK1 | SGK1 | Thr256 | EHNSTTStFCGTPEY | phosphorylation up-regulates | 10191262 | SIGNOR-236796 |
| PDPK1 | PDPK1 | Ser241 | SKQARANsFVGTAQY | phosphorylation down-regulates quantity by destabilization | 12177059 | SIGNOR-250077 |
| PDPK1 | RPS6KB1 | Thr252 | HDGTVTHtFCGTIEY | phosphorylation up-regulates activity | 9445476 | SIGNOR-243338 |
| PDPK1 | RPS6KB2 | Thr228 | HEGAVTHtFCGTIEY | phosphorylation up-regulates | 9445476 | SIGNOR-55371 |
| PDPK1 | TSSK3 | Thr168 | SHRELSQtFCGSTAY | phosphorylation up-regulates activity | 16336268 | SIGNOR-260786 |
| PDPK1 | AKT2 | Thr309 | SDGATMKtFCGTPEY | phosphorylation up-regulates activity | 15743829 | SIGNOR-134485 |
| PDPK1 | RPS6KB1 | Thr412 | NQVFLGFtYVAPSVL | phosphorylation up-regulates | 9445476 | SIGNOR-55310 |
| PDPK1 | MEK1/2 | – | phosphorylation up-regulates | 15175348 | SIGNOR-244938 | |
| PDPK1 | SGK2 | Thr193 | EPEDTTStFCGTPEY | phosphorylation up-regulates activity | 10548550 | SIGNOR-250277 |
| PDPK1 | AKT | Thr308 | KDGATMKtFCGTPEY | phosphorylation up-regulates activity | 12808134 | SIGNOR-134477 |
| PDPK1 | PRKCZ | Thr410 | GPGDTTStFCGTPNY | phosphorylation up-regulates | 11141077 | SIGNOR-85501 |
| PDPK1 | OXTR | – | phosphorylation up-regulates activity | 35104164 | SIGNOR-268577 | |
| PDPK1 | SGK3 | Thr320 | AISDTTTtFCGTPEY | phosphorylation up-regulates | 16790420 | SIGNOR-147213 |
| PDPK1 | PDPK1 | Ser241 | SKQARANsFVGTAQY | phosphorylation up-regulates activity | 10455013 | SIGNOR-236789 |
| PDPK1 | AKT1 | Thr308 | KDGATMKtFCGTPEY | phosphorylation up-regulates | 21798082 | SIGNOR-175675 |
| PDPK1 | PRKCB | Thr500 | WDGVTTKtFCGTPDY | phosphorylation up-regulates | 17115692 | SIGNOR-150857 |
| PDPK1 | PRKCB | – | phosphorylation up-regulates | 15209375 | SIGNOR-126069 | |
| PDPK1 | MEK1/2 | – | phosphorylation up-regulates activity | 15175348 | SIGNOR-244934 | |
| PDPK1 | PRKCA | – | phosphorylation up-regulates | 15209375 | SIGNOR-126066 | |
| PDPK1 | RPS6KB1 | Thr252 | HDGTVTHtFCGTIEY | phosphorylation up-regulates | 9445476 | SIGNOR-55306 |
| PDPK1 | IKBKB | Ser181 | DQGSLCTsFVGTLQY | phosphorylation up-regulates activity | 16207722 | SIGNOR-279088 |
| PDPK1 | PGK1 | Thr243 | IGGGMAFtFLKVLNN | phosphorylation up-regulates activity | 30029001 | SIGNOR-277402 |
| PDPK1 | PRKCG | – | phosphorylation up-regulates | 15209375 | SIGNOR-126072 | |
| PDPK1 | RPS6KB2 | Thr228 | HEGAVTHtFCGTIEY | phosphorylation up-regulates | 15209375 | SIGNOR-126076 |
| PDPK1 | RPS6KB2 | Thr388 | NQAFLGFtYVAPSVL | phosphorylation up-regulates activity | 11733037 | SIGNOR-250272 |
| PDPK1 | SGK1 | Thr256 | EHNSTTStFCGTPEY | phosphorylation up-regulates | 12387817 | SIGNOR-236800 |
| PDPK1 | PRKCD | Thr507 | FGESRAStFCGTPDY | phosphorylation up-regulates activity | 9748166 | SIGNOR-250269 |
| PDPK1 | AKT | – | phosphorylation up-regulates activity | 15743829 | SIGNOR-244469 | |
| PDPK1 | AKT1 | Thr308 | KDGATMKtFCGTPEY | phosphorylation up-regulates activity | 15718470 | SIGNOR-252612 |
| PDPK1 | AHCYL1 | Ser68 | RSLSRSIsQSSTDSY | phosphorylation down-regulates activity | 17635105 | SIGNOR-249174 |
| PDPK1 | RPS6KB2 | Ser370 | TRQTPVDsPDDTALS | phosphorylation up-regulates activity | 11733037 | SIGNOR-250371 |
| PDPK1 | RPS6KA3 | Ser227 | DHEKKAYsFCGTVEY | phosphorylation up-regulates | 19956600 | SIGNOR-161924 |
| PDPK1 | SGK3 | Thr320 | AISDTTTtFCGTPEY | phosphorylation up-regulates activity | 10548550 | SIGNOR-250279 |
| PDPK1 | PAK1 | Thr423 | PEQSKRStMVGTPYW | phosphorylation up-regulates activity | 10995762 | SIGNOR-250267 |
| PDPK1 | RPS6KB1 | Thr412 | NQVFLGFtYVAPSVL | phosphorylation up-regulates | 9445476 | SIGNOR-188911 |
| PDPK1 | AKT2 | Thr309 | SDGATMKtFCGTPEY | phosphorylation up-regulates activity | 9512493 | SIGNOR-236785 |
| PDPK1 | PDPK1 | Ser410 | GLPQRSGsNIEQYIH | phosphorylation unknown | 10455013 | SIGNOR-236772 |
| PDPK1 | CARD11 | – | phosphorylation up-regulates | 15802604 | SIGNOR-134866 | |
| PDPK1 | AKT1 | Ser473 | RPHFPQFsYSASGTA | phosphorylation up-regulates | 10226025 | SIGNOR-67367 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PDPK1 | phosphorylation up-regulates → | RPS6K PSer221 | phosphorylation up-regulates → | RPS6K | 10480933 | SIGNOR-252763 |
| PDPK1 | phosphorylation up-regulates → | RPS6KB1 PThr252 | phosphorylation up-regulates → | RPS6KB1 | 19864428 | SIGNOR-188907 |
| PDPK1 | phosphorylation up-regulates → | RPS6KA3 PSer227 | phosphorylation up-regulates → | RPS6KA3 | 10480933 | SIGNOR-70612 |
| PDPK1 | phosphorylation up-regulates → | PRKCE PThr566 | phosphorylation up-regulates → | PRKCE | 11964154 | SIGNOR-117320 |
| PDPK1 | phosphorylation up-regulates → | RPS6KB2 PThr228 | phosphorylation up-regulates → | RPS6KB2 | 11733037 | SIGNOR-250273 |
| PDPK1 | phosphorylation up-regulates → | PDPK1 PSer241 | phosphorylation up-regulates → | PDPK1 | 11481331 | SIGNOR-250268 |
| PDPK1 | phosphorylation up-regulates → | AKT2 PSer474 | phosphorylation up-regulates → | AKT2 | 15743829 | SIGNOR-134481 |
| PDPK1 | phosphorylation up-regulates → | AKT1 PThr308 | phosphorylation up-regulates → | AKT1 | 12167717 | SIGNOR-91354 |
| PDPK1 | phosphorylation up-regulates → | SGK2 PSer416 | phosphorylation up-regulates → | SGK2 | 10548550 | SIGNOR-250376 |
| PDPK1 | phosphorylation up-regulates → | RPS6KA1 PSer221 | phosphorylation up-regulates → | RPS6KA1 | 10480933 | SIGNOR-250270 |
| PDPK1 | phosphorylation up-regulates → | AKT1 PThr308 | phosphorylation up-regulates → | AKT1 | 10226025 | SIGNOR-67363 |
| PDPK1 | phosphorylation up-regulates → | PKN2 PThr816 | phosphorylation up-regulates → | PKN2 | 10753910 | SIGNOR-76710 |
| PDPK1 | phosphorylation up-regulates → | AKT1 PThr308 | phosphorylation up-regulates → | AKT1 | 19951971 | SIGNOR-249629 |
| PDPK1 | phosphorylation up-regulates → | SGK3 PSer486 | phosphorylation up-regulates → | SGK3 | 10548550 | SIGNOR-250278 |
| PDPK1 | phosphorylation up-regulates → | AKT PThr308 | phosphorylation up-regulates → | AKT | 9512493 | SIGNOR-244480 |
| PDPK1 | phosphorylation up-regulates → | MAP2K1 PSer222 | phosphorylation up-regulates → | MAP2K1 | 15175348 | SIGNOR-236633 |
| PDPK1 | phosphorylation up-regulates → | ITGB3 PThr779 | phosphorylation down-regulates ⊣ | ITGB3 | 10896934 | SIGNOR-250266 |
| PDPK1 | phosphorylation up-regulates → | SGK1 PThr256 | phosphorylation up-regulates → | SGK1 | 15209375 | SIGNOR-236637 |
| PDPK1 | phosphorylation up-regulates → | AKT1 PThr308 | phosphorylation up-regulates → | AKT1 | 12808134 | SIGNOR-252611 |
| PDPK1 | phosphorylation up-regulates → | SGK1 PSer422 | phosphorylation up-regulates → | SGK1 | 10191262 | SIGNOR-250274 |
| PDPK1 | phosphorylation up-regulates → | AKT3 PThr305 | phosphorylation up-regulates → | AKT3 | 9512493 | SIGNOR-55937 |
| PDPK1 | phosphorylation up-regulates → | AKT PThr308 | phosphorylation up-regulates → | AKT | 15718470 | SIGNOR-243203 |
| PDPK1 | phosphorylation up-regulates → | AKT PThr308 | phosphorylation up-regulates → | AKT | 10226025 | SIGNOR-244421 |
| PDPK1 | phosphorylation up-regulates → | SGK1 PThr256 | phosphorylation up-regulates → | SGK1 | 10191262 | SIGNOR-250275 |
| PDPK1 | phosphorylation up-regulates → | PDPK1 PSer396 | phosphorylation down-regulates ⊣ | PDPK1 | 10455013 | SIGNOR-236764 |
| PDPK1 | phosphorylation up-regulates → | PKN1 PThr774 | phosphorylation up-regulates → | PKN1 | 10753910 | SIGNOR-76640 |
| PDPK1 | phosphorylation up-regulates → | MAP2K2 PSer226 | phosphorylation up-regulates → | MAP2K2 | 15175348 | SIGNOR-125176 |
| PDPK1 | phosphorylation up-regulates → | PDPK1 PSer25 | phosphorylation down-regulates ⊣ | PDPK1 | 10455013 | SIGNOR-236777 |
| PDPK1 | phosphorylation up-regulates → | PDPK1 PSer393 | phosphorylation down-regulates ⊣ | PDPK1 | 10455013 | SIGNOR-235782 |
| PDPK1 | phosphorylation up-regulates → | SGK1 PThr256 | phosphorylation up-regulates → | SGK1 | 10191262 | SIGNOR-236796 |
| PDPK1 | phosphorylation up-regulates → | PDPK1 PSer241 | phosphorylation down-regulates ⊣ | PDPK1 | 12177059 | SIGNOR-250077 |
| PDPK1 | phosphorylation up-regulates → | RPS6KB1 PThr252 | phosphorylation up-regulates → | RPS6KB1 | 9445476 | SIGNOR-243338 |
| PDPK1 | phosphorylation up-regulates → | RPS6KB2 PThr228 | phosphorylation up-regulates → | RPS6KB2 | 9445476 | SIGNOR-55371 |
| PDPK1 | phosphorylation up-regulates → | TSSK3 PThr168 | phosphorylation up-regulates → | TSSK3 | 16336268 | SIGNOR-260786 |
| PDPK1 | phosphorylation up-regulates → | AKT2 PThr309 | phosphorylation up-regulates → | AKT2 | 15743829 | SIGNOR-134485 |
| PDPK1 | phosphorylation up-regulates → | RPS6KB1 PThr412 | phosphorylation up-regulates → | RPS6KB1 | 9445476 | SIGNOR-55310 |
| PDPK1 | phosphorylation up-regulates → | SGK2 PThr193 | phosphorylation up-regulates → | SGK2 | 10548550 | SIGNOR-250277 |
| PDPK1 | phosphorylation up-regulates → | AKT PThr308 | phosphorylation up-regulates → | AKT | 12808134 | SIGNOR-134477 |
| PDPK1 | phosphorylation up-regulates → | PRKCZ PThr410 | phosphorylation up-regulates → | PRKCZ | 11141077 | SIGNOR-85501 |
| PDPK1 | phosphorylation up-regulates → | SGK3 PThr320 | phosphorylation up-regulates → | SGK3 | 16790420 | SIGNOR-147213 |
| PDPK1 | phosphorylation up-regulates → | PDPK1 PSer241 | phosphorylation up-regulates → | PDPK1 | 10455013 | SIGNOR-236789 |
| PDPK1 | phosphorylation up-regulates → | AKT1 PThr308 | phosphorylation up-regulates → | AKT1 | 21798082 | SIGNOR-175675 |
| PDPK1 | phosphorylation up-regulates → | PRKCB PThr500 | phosphorylation up-regulates → | PRKCB | 17115692 | SIGNOR-150857 |
| PDPK1 | phosphorylation up-regulates → | RPS6KB1 PThr252 | phosphorylation up-regulates → | RPS6KB1 | 9445476 | SIGNOR-55306 |
| PDPK1 | phosphorylation up-regulates → | IKBKB PSer181 | phosphorylation up-regulates → | IKBKB | 16207722 | SIGNOR-279088 |
| PDPK1 | phosphorylation up-regulates → | PGK1 PThr243 | phosphorylation up-regulates → | PGK1 | 30029001 | SIGNOR-277402 |
| PDPK1 | phosphorylation up-regulates → | RPS6KB2 PThr228 | phosphorylation up-regulates → | RPS6KB2 | 15209375 | SIGNOR-126076 |
| PDPK1 | phosphorylation up-regulates → | RPS6KB2 PThr388 | phosphorylation up-regulates → | RPS6KB2 | 11733037 | SIGNOR-250272 |
| PDPK1 | phosphorylation up-regulates → | SGK1 PThr256 | phosphorylation up-regulates → | SGK1 | 12387817 | SIGNOR-236800 |
| PDPK1 | phosphorylation up-regulates → | PRKCD PThr507 | phosphorylation up-regulates → | PRKCD | 9748166 | SIGNOR-250269 |
| PDPK1 | phosphorylation up-regulates → | AKT1 PThr308 | phosphorylation up-regulates → | AKT1 | 15718470 | SIGNOR-252612 |
| PDPK1 | phosphorylation up-regulates → | AHCYL1 PSer68 | phosphorylation down-regulates ⊣ | AHCYL1 | 17635105 | SIGNOR-249174 |
| PDPK1 | phosphorylation up-regulates → | RPS6KB2 PSer370 | phosphorylation up-regulates → | RPS6KB2 | 11733037 | SIGNOR-250371 |
| PDPK1 | phosphorylation up-regulates → | RPS6KA3 PSer227 | phosphorylation up-regulates → | RPS6KA3 | 19956600 | SIGNOR-161924 |
| PDPK1 | phosphorylation up-regulates → | SGK3 PThr320 | phosphorylation up-regulates → | SGK3 | 10548550 | SIGNOR-250279 |
| PDPK1 | phosphorylation up-regulates → | PAK1 PThr423 | phosphorylation up-regulates → | PAK1 | 10995762 | SIGNOR-250267 |
| PDPK1 | phosphorylation up-regulates → | RPS6KB1 PThr412 | phosphorylation up-regulates → | RPS6KB1 | 9445476 | SIGNOR-188911 |
| PDPK1 | phosphorylation up-regulates → | AKT2 PThr309 | phosphorylation up-regulates → | AKT2 | 9512493 | SIGNOR-236785 |
| PDPK1 | phosphorylation up-regulates → | PDPK1 PSer410 | phosphorylation down-regulates ⊣ | PDPK1 | 10455013 | SIGNOR-236772 |
| PDPK1 | phosphorylation up-regulates → | AKT1 PSer473 | phosphorylation up-regulates → | AKT1 | 10226025 | SIGNOR-67367 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PDPK1 | phosphorylation → up-regulates activity | RPS6K | SIGNOR-252763 |
| PDPK1 | phosphorylation → up-regulates | RPS6KB1 | SIGNOR-188907 |
| PDPK1 | phosphorylation → up-regulates | RPS6KA3 | SIGNOR-70612 |
| PDPK1 | phosphorylation → up-regulates | PRKCE | SIGNOR-117320 |
| PDPK1 | phosphorylation → up-regulates activity | RPS6KB2 | SIGNOR-250273 |
| PDPK1 | phosphorylation → up-regulates activity | PDPK1 | SIGNOR-250268 |
| PDPK1 | phosphorylation → up-regulates activity | PRKCH | SIGNOR-280062 |
| PDPK1 | phosphorylation → up-regulates activity | RAF1 | SIGNOR-280063 |
| PDPK1 | phosphorylation → up-regulates activity | AKT2 | SIGNOR-134481 |
| PDPK1 | phosphorylation → up-regulates | AKT1 | SIGNOR-91354 |
| PDPK1 | phosphorylation → up-regulates activity | SGK2 | SIGNOR-250376 |
| PDPK1 | phosphorylation → up-regulates activity | RPS6KA1 | SIGNOR-250270 |
| PDPK1 | phosphorylation → up-regulates | AKT | SIGNOR-244396 |
| PDPK1 | phosphorylation → up-regulates | AKT1 | SIGNOR-67363 |
| PDPK1 | phosphorylation → up-regulates | PKN2 | SIGNOR-76710 |
| PDPK1 | phosphorylation → up-regulates activity | AKT1 | SIGNOR-249629 |
| PDPK1 | phosphorylation → up-regulates | PRKCQ | SIGNOR-134869 |
| PDPK1 | phosphorylation → up-regulates activity | PLK1 | SIGNOR-243519 |
| PDPK1 | phosphorylation → up-regulates | SGK3 | SIGNOR-126236 |
| PDPK1 | phosphorylation → up-regulates activity | SGK3 | SIGNOR-250278 |
| PDPK1 | phosphorylation → up-regulates activity | AKT | SIGNOR-244480 |
| PDPK1 | phosphorylation → up-regulates activity | MAP2K1 | SIGNOR-236633 |
| PDPK1 | phosphorylation → up-regulates | SGK2 | SIGNOR-126177 |
| PDPK1 | phosphorylation → down-regulates activity | ITGB3 | SIGNOR-250266 |
| PDPK1 | phosphorylation → up-regulates | SGK1 | SIGNOR-236637 |
| PDPK1 | phosphorylation → up-regulates | AKT1 | SIGNOR-252611 |
| PDPK1 | phosphorylation → up-regulates activity | SGK1 | SIGNOR-250274 |
| PDPK1 | phosphorylation → up-regulates | AKT3 | SIGNOR-55937 |
| PDPK1 | phosphorylation → up-regulates activity | AKT | SIGNOR-243203 |
| PDPK1 | phosphorylation → up-regulates activity | AKT | SIGNOR-244421 |
| PDPK1 | phosphorylation → up-regulates activity | SGK1 | SIGNOR-250275 |
| PDPK1 | phosphorylation → unknown | PDPK1 | SIGNOR-236764 |
| PDPK1 | phosphorylation → up-regulates | PKN1 | SIGNOR-76640 |
| PDPK1 | phosphorylation → up-regulates | MAP2K2 | SIGNOR-125176 |
| PDPK1 | phosphorylation → unknown | PDPK1 | SIGNOR-236777 |
| PDPK1 | phosphorylation → unknown | PDPK1 | SIGNOR-235782 |
| PDPK1 | phosphorylation → up-regulates | SGK1 | SIGNOR-236796 |
| PDPK1 | phosphorylation down-regulates quantity by destabilization | PDPK1 | SIGNOR-250077 |
| PDPK1 | phosphorylation → up-regulates activity | RPS6KB1 | SIGNOR-243338 |
| PDPK1 | phosphorylation → up-regulates | RPS6KB2 | SIGNOR-55371 |
| PDPK1 | phosphorylation → up-regulates activity | TSSK3 | SIGNOR-260786 |
| PDPK1 | phosphorylation → up-regulates activity | AKT2 | SIGNOR-134485 |
| PDPK1 | phosphorylation → up-regulates | RPS6KB1 | SIGNOR-55310 |
| PDPK1 | phosphorylation → up-regulates | MEK1/2 | SIGNOR-244938 |
| PDPK1 | phosphorylation → up-regulates activity | SGK2 | SIGNOR-250277 |
| PDPK1 | phosphorylation → up-regulates activity | AKT | SIGNOR-134477 |
| PDPK1 | phosphorylation → up-regulates | PRKCZ | SIGNOR-85501 |
| PDPK1 | phosphorylation → up-regulates activity | OXTR | SIGNOR-268577 |
| PDPK1 | phosphorylation → up-regulates | SGK3 | SIGNOR-147213 |
| PDPK1 | phosphorylation → up-regulates activity | PDPK1 | SIGNOR-236789 |
| PDPK1 | phosphorylation → up-regulates | AKT1 | SIGNOR-175675 |
| PDPK1 | phosphorylation → up-regulates | PRKCB | SIGNOR-150857 |
| PDPK1 | phosphorylation → up-regulates | PRKCB | SIGNOR-126069 |
| PDPK1 | phosphorylation → up-regulates activity | MEK1/2 | SIGNOR-244934 |
| PDPK1 | phosphorylation → up-regulates | PRKCA | SIGNOR-126066 |
| PDPK1 | phosphorylation → up-regulates | RPS6KB1 | SIGNOR-55306 |
| PDPK1 | phosphorylation → up-regulates activity | IKBKB | SIGNOR-279088 |
| PDPK1 | phosphorylation → up-regulates activity | PGK1 | SIGNOR-277402 |
| PDPK1 | phosphorylation → up-regulates | PRKCG | SIGNOR-126072 |
| PDPK1 | phosphorylation → up-regulates | RPS6KB2 | SIGNOR-126076 |
| PDPK1 | phosphorylation → up-regulates activity | RPS6KB2 | SIGNOR-250272 |
| PDPK1 | phosphorylation → up-regulates | SGK1 | SIGNOR-236800 |
| PDPK1 | phosphorylation → up-regulates activity | PRKCD | SIGNOR-250269 |
| PDPK1 | phosphorylation → up-regulates activity | AKT | SIGNOR-244469 |
| PDPK1 | phosphorylation → up-regulates activity | AKT1 | SIGNOR-252612 |
| PDPK1 | phosphorylation → down-regulates activity | AHCYL1 | SIGNOR-249174 |
| PDPK1 | phosphorylation → up-regulates activity | RPS6KB2 | SIGNOR-250371 |
| PDPK1 | phosphorylation → up-regulates | RPS6KA3 | SIGNOR-161924 |
| PDPK1 | phosphorylation → up-regulates activity | SGK3 | SIGNOR-250279 |
| PDPK1 | phosphorylation → up-regulates activity | PAK1 | SIGNOR-250267 |
| PDPK1 | phosphorylation → up-regulates | RPS6KB1 | SIGNOR-188911 |
| PDPK1 | phosphorylation → up-regulates activity | AKT2 | SIGNOR-236785 |
| PDPK1 | phosphorylation → unknown | PDPK1 | SIGNOR-236772 |
| PDPK1 | phosphorylation → up-regulates | CARD11 | SIGNOR-134866 |
| PDPK1 | phosphorylation → up-regulates | AKT1 | SIGNOR-67367 |