| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PDPK1 | PDPK1 | Ser241 | SKQARANsFVGTAQY | phosphorylation down-regulates quantity by destabilization | 12177059 | SIGNOR-250077 |
| PDPK1 | PDPK1 | Ser241 | SKQARANsFVGTAQY | phosphorylation up-regulates activity | 10455013 | SIGNOR-236789 |
| PDPK1 | PDPK1 | Ser241 | SKQARANsFVGTAQY | phosphorylation up-regulates activity | 11481331 | SIGNOR-250268 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PDPK1 | phosphorylation up-regulates → | PDPK1 PSer241 | phosphorylation down-regulates ⊣ | PDPK1 | 12177059 | SIGNOR-250077 |
| PDPK1 | phosphorylation up-regulates → | PDPK1 PSer241 | phosphorylation up-regulates → | PDPK1 | 10455013 | SIGNOR-236789 |
| PDPK1 | phosphorylation up-regulates → | PDPK1 PSer241 | phosphorylation up-regulates → | PDPK1 | 11481331 | SIGNOR-250268 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PDPK1 | phosphorylation![]() down-regulates quantity by destabilization | PDPK1 | SIGNOR-250077 |
| PDPK1 | phosphorylation → up-regulates activity | PDPK1 | SIGNOR-236789 |
| PDPK1 | phosphorylation → up-regulates activity | PDPK1 | SIGNOR-250268 |