| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK2 | CCP110 | Ser45 | FHGVAILsPLLNIEK | phosphorylation down-regulates activity | 12361598 | SIGNOR-265957 |
| CDK2 | CCP110 | Ser372 | PSPEPSMsPKMHRRR | phosphorylation down-regulates activity | 12361598 | SIGNOR-265962 |
| CDK2 | CCP110 | Ser366 | GSYAKLPsPEPSMSP | phosphorylation down-regulates activity | 12361598 | SIGNOR-265960 |
| CDK2 | CCP110 | Ser400 | PINACELsPKGKEQA | phosphorylation down-regulates activity | 12361598 | SIGNOR-265956 |
| CDK2 | CCP110 | Thr566 | NTRQQMDtPMVSCGN | phosphorylation down-regulates activity | 12361598 | SIGNOR-265959 |
| CDK2 | CCP110 | Ser170 | RDSEGFNsPKQCDSS | phosphorylation down-regulates activity | 12361598 | SIGNOR-265958 |
| CDK2 | CCP110 | Thr194 | FPKTSSAtPQETLIS | phosphorylation down-regulates activity | 12361598 | SIGNOR-265961 |
| CDK2 | CCP110 | Ser516 | ASSQCIAsPNFGTVS | phosphorylation down-regulates activity | 12361598 | SIGNOR-265963 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK2 | phosphorylation up-regulates → | CCP110 PSer45 | phosphorylation down-regulates ⊣ | CCP110 | 12361598 | SIGNOR-265957 |
| CDK2 | phosphorylation up-regulates → | CCP110 PSer372 | phosphorylation down-regulates ⊣ | CCP110 | 12361598 | SIGNOR-265962 |
| CDK2 | phosphorylation up-regulates → | CCP110 PSer366 | phosphorylation down-regulates ⊣ | CCP110 | 12361598 | SIGNOR-265960 |
| CDK2 | phosphorylation up-regulates → | CCP110 PSer400 | phosphorylation down-regulates ⊣ | CCP110 | 12361598 | SIGNOR-265956 |
| CDK2 | phosphorylation up-regulates → | CCP110 PThr566 | phosphorylation down-regulates ⊣ | CCP110 | 12361598 | SIGNOR-265959 |
| CDK2 | phosphorylation up-regulates → | CCP110 PSer170 | phosphorylation down-regulates ⊣ | CCP110 | 12361598 | SIGNOR-265958 |
| CDK2 | phosphorylation up-regulates → | CCP110 PThr194 | phosphorylation down-regulates ⊣ | CCP110 | 12361598 | SIGNOR-265961 |
| CDK2 | phosphorylation up-regulates → | CCP110 PSer516 | phosphorylation down-regulates ⊣ | CCP110 | 12361598 | SIGNOR-265963 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CDK2 | phosphorylation → down-regulates activity | CCP110 | SIGNOR-265957 |
| CDK2 | phosphorylation → down-regulates activity | CCP110 | SIGNOR-265962 |
| CDK2 | phosphorylation → down-regulates activity | CCP110 | SIGNOR-265960 |
| CDK2 | phosphorylation → down-regulates activity | CCP110 | SIGNOR-265956 |
| CDK2 | phosphorylation → down-regulates activity | CCP110 | SIGNOR-265959 |
| CDK2 | phosphorylation → down-regulates activity | CCP110 | SIGNOR-265958 |
| CDK2 | phosphorylation → down-regulates activity | CCP110 | SIGNOR-265961 |
| CDK2 | phosphorylation → down-regulates activity | CCP110 | SIGNOR-265963 |
