Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
PPM1B	MAP3K7	–		dephosphorylation down-regulates activity	11104763	SIGNOR-277154
PPP6C	MAP3K7	Thr187	CDIQTHMtNNKGSAA	dephosphorylation down-regulates	17079228	SIGNOR-150408
PTPN6	MAP3K7	–		dephosphorylation down-regulates activity	31130074	SIGNOR-277128
MAP3K7	MAP3K7	Thr187	CDIQTHMtNNKGSAA	phosphorylation up-regulates activity	20538596	SIGNOR-227540
FGFR3	MAP3K7	–		phosphorylation up-regulates activity	24466111	SIGNOR-279176
CAMK2G	MAP3K7	–		phosphorylation up-regulates	12482967	SIGNOR-96422
MAP3K7	MAP3K7	Thr184	GTACDIQtHMTNNKG	phosphorylation up-regulates activity	20538596	SIGNOR-227544
PPM1F	MAP3K7	–		dephosphorylation down-regulates activity	28906490	SIGNOR-277047
PPP2CA	MAP3K7	Thr187	CDIQTHMtNNKGSAA	dephosphorylation down-regulates	17079228	SIGNOR-150369
MAP3K7	MAP3K7	Thr178	LKICDFGtACDIQTH	phosphorylation up-regulates activity	20538596	SIGNOR-227536
PPP6C	MAP3K7	Thr187	CDIQTHMtNNKGSAA	dephosphorylation down-regulates activity	17079228	SIGNOR-248292
MAP3K7	MAP3K7	Ser192 View in OncoXplorer	HMTNNKGsAAWMAPE	phosphorylation up-regulates activity	20538596	SIGNOR-232153
PINK1	MAP3K7	–		phosphorylation up-regulates activity	22643835	SIGNOR-279644
PPM1L	MAP3K7	–		dephosphorylation down-regulates activity	12556533	SIGNOR-277114
MAP3K7	MAP3K7	Ser192 View in OncoXplorer	HMTNNKGsAAWMAPE	phosphorylation up-regulates activity	10702308	SIGNOR-235758

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
PPP6C	dephosphorylation down-regulates ⊣	MAP3K7 PThr187	dephosphorylation up-regulates →	MAP3K7	17079228	SIGNOR-150408
MAP3K7	phosphorylation up-regulates →	MAP3K7 PThr187	phosphorylation up-regulates →	MAP3K7	20538596	SIGNOR-227540
MAP3K7	phosphorylation up-regulates →	MAP3K7 PThr184	phosphorylation up-regulates →	MAP3K7	20538596	SIGNOR-227544
PPP2CA	dephosphorylation down-regulates ⊣	MAP3K7 PThr187	dephosphorylation up-regulates →	MAP3K7	17079228	SIGNOR-150369
MAP3K7	phosphorylation up-regulates →	MAP3K7 PThr178	phosphorylation up-regulates →	MAP3K7	20538596	SIGNOR-227536
PPP6C	dephosphorylation down-regulates ⊣	MAP3K7 PThr187	dephosphorylation up-regulates →	MAP3K7	17079228	SIGNOR-248292
MAP3K7	phosphorylation up-regulates →	MAP3K7 PSer192	phosphorylation up-regulates →	MAP3K7	20538596	SIGNOR-232153
MAP3K7	phosphorylation up-regulates →	MAP3K7 PSer192	phosphorylation up-regulates →	MAP3K7	10702308	SIGNOR-235758

Regulator	Mechanism/Effect	Target	SIGNOR-ID
PPM1B	dephosphorylation → down-regulates activity	MAP3K7	SIGNOR-277154
PPP6C	dephosphorylation down-regulates	MAP3K7	SIGNOR-150408
PTPN6	dephosphorylation → down-regulates activity	MAP3K7	SIGNOR-277128
MAP3K7	phosphorylation → up-regulates activity	MAP3K7	SIGNOR-227540
FGFR3	phosphorylation → up-regulates activity	MAP3K7	SIGNOR-279176
CAMK2G	phosphorylation → up-regulates	MAP3K7	SIGNOR-96422
MAP3K7	phosphorylation → up-regulates activity	MAP3K7	SIGNOR-227544
PPM1F	dephosphorylation → down-regulates activity	MAP3K7	SIGNOR-277047
PPP2CA	dephosphorylation down-regulates	MAP3K7	SIGNOR-150369
MAP3K7	phosphorylation → up-regulates activity	MAP3K7	SIGNOR-227536
PPP6C	dephosphorylation → down-regulates activity	MAP3K7	SIGNOR-248292
MAP3K7	phosphorylation → up-regulates activity	MAP3K7	SIGNOR-232153
PINK1	phosphorylation → up-regulates activity	MAP3K7	SIGNOR-279644
PPM1L	dephosphorylation → down-regulates activity	MAP3K7	SIGNOR-277114
MAP3K7	phosphorylation → up-regulates activity	MAP3K7	SIGNOR-235758