Entity Details

Name PPP2CA_Thr187
ID O43318
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PPP2CAMAP3K7Thr187CDIQTHMtNNKGSAAdephosphorylation
down-regulates		17079228SIGNOR-150369
PPP6CMAP3K7Thr187CDIQTHMtNNKGSAAdephosphorylation
down-regulates activity		17079228SIGNOR-248292
PPP6CMAP3K7Thr187CDIQTHMtNNKGSAAdephosphorylation
down-regulates		17079228SIGNOR-150408
MAP3K7MAP3K7Thr187CDIQTHMtNNKGSAAphosphorylation
up-regulates activity		20538596SIGNOR-227540
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PPP2CAdephosphorylation
down-regulates
⊣
MAP3K7
PThr187		dephosphorylation
up-regulates
→		MAP3K717079228SIGNOR-150369
PPP6Cdephosphorylation
down-regulates
⊣
MAP3K7
PThr187		dephosphorylation
up-regulates
→		MAP3K717079228SIGNOR-248292
PPP6Cdephosphorylation
down-regulates
⊣
MAP3K7
PThr187		dephosphorylation
up-regulates
→		MAP3K717079228SIGNOR-150408
MAP3K7phosphorylation
up-regulates
→
MAP3K7
PThr187		phosphorylation
up-regulates
→		MAP3K720538596SIGNOR-227540
Regulator Mechanism/Effect Target SIGNOR-ID
PPP2CAdephosphorylation
img/direct_inhibition.png
down-regulates 		MAP3K7SIGNOR-150369
PPP6Cdephosphorylation
→
down-regulates activity 		MAP3K7SIGNOR-248292
PPP6Cdephosphorylation
img/direct_inhibition.png
down-regulates 		MAP3K7SIGNOR-150408
MAP3K7phosphorylation
→
up-regulates activity 		MAP3K7SIGNOR-227540