| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SRC | PROM1 | Tyr852 | GYHKDHVyGIHNPVM | phosphorylation unknown | 19296573 | SIGNOR-184776 |
| SRC | PROM1 | Tyr828 | RMDSEDVyDDVETIP | phosphorylation unknown | 19296573 | SIGNOR-184772 |
| PTPRK | PROM1 | – | dephosphorylation down-regulates activity | 30947381 | SIGNOR-277133 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SRC | phosphorylation up-regulates → | PROM1 PTyr852 | phosphorylation down-regulates ⊣ | PROM1 | 19296573 | SIGNOR-184776 |
| SRC | phosphorylation up-regulates → | PROM1 PTyr828 | phosphorylation down-regulates ⊣ | PROM1 | 19296573 | SIGNOR-184772 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| SRC | phosphorylation → unknown | PROM1 | SIGNOR-184776 |
| SRC | phosphorylation → unknown | PROM1 | SIGNOR-184772 |
| PTPRK | dephosphorylation → down-regulates activity | PROM1 | SIGNOR-277133 |
