| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK10 | BCL2L11 | Ser69 | GPLAPPAsPGPFATR | phosphorylation down-regulates quantity by destabilization | 15486195 | SIGNOR-250080 |
| MAPK3 | BCL2L11 | Ser69 | GPLAPPAsPGPFATR | phosphorylation down-regulates quantity by destabilization | 15486195 | SIGNOR-129878 |
| p38 | BCL2L11 | Ser69 | GPLAPPAsPGPFATR | phosphorylation down-regulates quantity by destabilization | 15486195 | SIGNOR-260443 |
| MAPK8 | BCL2L11 | Ser69 | GPLAPPAsPGPFATR | phosphorylation down-regulates quantity by destabilization | 15486195 | SIGNOR-250132 |
| MAPK14 | BCL2L11 | Ser69 | GPLAPPAsPGPFATR | phosphorylation down-regulates quantity by destabilization | 15486195 | SIGNOR-260442 |
| MAPK8 | BCL2L11 | Ser69 | GPLAPPAsPGPFATR | phosphorylation down-regulates quantity by destabilization | 18174237 | SIGNOR-160323 |
| MAPK9 | BCL2L11 | Ser69 | GPLAPPAsPGPFATR | phosphorylation down-regulates quantity by destabilization | 18174237 | SIGNOR-250136 |
| MAPK1 | BCL2L11 | Ser69 | GPLAPPAsPGPFATR | phosphorylation down-regulates quantity by destabilization | 15486195 | SIGNOR-129874 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK10 | phosphorylation up-regulates → | BCL2L11 PSer69 | phosphorylation down-regulates ⊣ | BCL2L11 | 15486195 | SIGNOR-250080 |
| MAPK3 | phosphorylation up-regulates → | BCL2L11 PSer69 | phosphorylation down-regulates ⊣ | BCL2L11 | 15486195 | SIGNOR-129878 |
| p38 | phosphorylation up-regulates → | BCL2L11 PSer69 | phosphorylation down-regulates ⊣ | BCL2L11 | 15486195 | SIGNOR-260443 |
| MAPK8 | phosphorylation up-regulates → | BCL2L11 PSer69 | phosphorylation down-regulates ⊣ | BCL2L11 | 15486195 | SIGNOR-250132 |
| MAPK14 | phosphorylation up-regulates → | BCL2L11 PSer69 | phosphorylation down-regulates ⊣ | BCL2L11 | 15486195 | SIGNOR-260442 |
| MAPK8 | phosphorylation up-regulates → | BCL2L11 PSer69 | phosphorylation down-regulates ⊣ | BCL2L11 | 18174237 | SIGNOR-160323 |
| MAPK9 | phosphorylation up-regulates → | BCL2L11 PSer69 | phosphorylation down-regulates ⊣ | BCL2L11 | 18174237 | SIGNOR-250136 |
| MAPK1 | phosphorylation up-regulates → | BCL2L11 PSer69 | phosphorylation down-regulates ⊣ | BCL2L11 | 15486195 | SIGNOR-129874 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPK10 | phosphorylation down-regulates quantity by destabilization | BCL2L11 | SIGNOR-250080 |
| MAPK3 | phosphorylation down-regulates quantity by destabilization | BCL2L11 | SIGNOR-129878 |
| p38 | phosphorylation down-regulates quantity by destabilization | BCL2L11 | SIGNOR-260443 |
| MAPK8 | phosphorylation down-regulates quantity by destabilization | BCL2L11 | SIGNOR-250132 |
| MAPK14 | phosphorylation down-regulates quantity by destabilization | BCL2L11 | SIGNOR-260442 |
| MAPK8 | phosphorylation down-regulates quantity by destabilization | BCL2L11 | SIGNOR-160323 |
| MAPK9 | phosphorylation down-regulates quantity by destabilization | BCL2L11 | SIGNOR-250136 |
| MAPK1 | phosphorylation down-regulates quantity by destabilization | BCL2L11 | SIGNOR-129874 |
