Entity Details

Name AMPK_Ser588
ID O43524
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PRKAA1FOXO3Ser588QTLSDSLsGSSLYSTphosphorylation
up-regulates activity		17711846SIGNOR-249684
AMPKFOXO3Ser588QTLSDSLsGSSLYSTphosphorylation
up-regulates activity		17711846SIGNOR-274096
AMPKFOXO3Ser588QTLSDSLsGSSLYSTphosphorylation
up-regulates activity		17711846SIGNOR-249685
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PRKAA1phosphorylation
up-regulates
→
FOXO3
PSer588		phosphorylation
up-regulates
→		FOXO317711846SIGNOR-249684
AMPKphosphorylation
up-regulates
→
FOXO3
PSer588		phosphorylation
up-regulates
→		FOXO317711846SIGNOR-274096
AMPKphosphorylation
up-regulates
→
FOXO3
PSer588		phosphorylation
up-regulates
→		FOXO317711846SIGNOR-249685
Regulator Mechanism/Effect Target SIGNOR-ID
PRKAA1phosphorylation
→
up-regulates activity 		FOXO3SIGNOR-249684
AMPKphosphorylation
→
up-regulates activity 		FOXO3SIGNOR-274096
AMPKphosphorylation
→
up-regulates activity 		FOXO3SIGNOR-249685