| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| STK4 | FOXO3 | Ser209 | SSAGWKNsIRHNLSL | phosphorylation up-regulates | 22898666 | SIGNOR-191851 |
| STK4 | FOXO3 | Ser209 | SSAGWKNsIRHNLSL | phosphorylation up-regulates | 18394876 | SIGNOR-178190 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| STK4 | phosphorylation up-regulates → | FOXO3 PSer209 | phosphorylation up-regulates → | FOXO3 | 22898666 | SIGNOR-191851 |
| STK4 | phosphorylation up-regulates → | FOXO3 PSer209 | phosphorylation up-regulates → | FOXO3 | 18394876 | SIGNOR-178190 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| STK4 | phosphorylation → up-regulates | FOXO3 | SIGNOR-191851 |
| STK4 | phosphorylation → up-regulates | FOXO3 | SIGNOR-178190 |
