Entity Details

Name FYN_Tyr220
ID O43561
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
LCKLATTyr220SLDGSREyVNVSQELphosphorylation
up-regulates		16938345SIGNOR-149186
FYNLATTyr220SLDGSREyVNVSQELphosphorylation
up-regulates		16938345SIGNOR-148931
ZAP70LATTyr220SLDGSREyVNVSQELphosphorylation
up-regulates activity		11368773SIGNOR-247030
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
LCKphosphorylation
up-regulates
→
LAT
PTyr220		phosphorylation
up-regulates
→		LAT16938345SIGNOR-149186
FYNphosphorylation
up-regulates
→
LAT
PTyr220		phosphorylation
up-regulates
→		LAT16938345SIGNOR-148931
ZAP70phosphorylation
up-regulates
→
LAT
PTyr220		phosphorylation
up-regulates
→		LAT11368773SIGNOR-247030
Regulator Mechanism/Effect Target SIGNOR-ID
LCKphosphorylation
→
up-regulates 		LATSIGNOR-149186
FYNphosphorylation
→
up-regulates 		LATSIGNOR-148931
ZAP70phosphorylation
→
up-regulates activity 		LATSIGNOR-247030