Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
CDK5	PRKN	Ser131 View in OncoXplorer	HTDSRKDsPPAGSPA	phosphorylation down-regulates	17327227	SIGNOR-153445
PINK1	PRKN	Ser65	NCDLDQQsIVHIVQR	phosphorylation up-regulates activity	22724072	SIGNOR-270345
ABL1	PRKN	Tyr143	SPAGRSIyNSFYVYC	phosphorylation down-regulates	20823226	SIGNOR-167853
PINK1	PRKN	Ser65	NCDLDQQsIVHIVQR	phosphorylation up-regulates	22724072	SIGNOR-197976
PLK1	PRKN	Ser378	AYHEGECsAVFEASG	phosphorylation up-regulates activity	26387737	SIGNOR-276938
MTOR	PRKN	Ser127	AVILHTDsRKDSPPA	phosphorylation down-regulates activity	35191952	SIGNOR-277586
ULK1	PRKN	Ser108	SLTRVDLsSSVLPGD	phosphorylation up-regulates activity	33827825	SIGNOR-279663

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
CDK5	phosphorylation up-regulates →	PRKN PSer131	phosphorylation down-regulates ⊣	PRKN	17327227	SIGNOR-153445
PINK1	phosphorylation up-regulates →	PRKN PSer65	phosphorylation up-regulates →	PRKN	22724072	SIGNOR-270345
ABL1	phosphorylation up-regulates →	PRKN PTyr143	phosphorylation down-regulates ⊣	PRKN	20823226	SIGNOR-167853
PINK1	phosphorylation up-regulates →	PRKN PSer65	phosphorylation up-regulates →	PRKN	22724072	SIGNOR-197976
PLK1	phosphorylation up-regulates →	PRKN PSer378	phosphorylation up-regulates →	PRKN	26387737	SIGNOR-276938
MTOR	phosphorylation up-regulates →	PRKN PSer127	phosphorylation down-regulates ⊣	PRKN	35191952	SIGNOR-277586
ULK1	phosphorylation up-regulates →	PRKN PSer108	phosphorylation up-regulates →	PRKN	33827825	SIGNOR-279663

Regulator	Mechanism/Effect	Target	SIGNOR-ID
CDK5	phosphorylation down-regulates	PRKN	SIGNOR-153445
PINK1	phosphorylation → up-regulates activity	PRKN	SIGNOR-270345
ABL1	phosphorylation down-regulates	PRKN	SIGNOR-167853
PINK1	phosphorylation → up-regulates	PRKN	SIGNOR-197976
PLK1	phosphorylation → up-regulates activity	PRKN	SIGNOR-276938
MTOR	phosphorylation → down-regulates activity	PRKN	SIGNOR-277586
ULK1	phosphorylation → up-regulates activity	PRKN	SIGNOR-279663