Entity Details

Name EGFR_Tyr228
ID O60716
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CSF1RCTNND1Tyr228YPGGSDNyGSLSRVTphosphorylation
up-regulates quantity by stabilization		21049007SIGNOR-278928
SRCCTNND1Tyr228YPGGSDNyGSLSRVTphosphorylation
up-regulates activity		11382764SIGNOR-246484
EGFRCTNND1Tyr228YPGGSDNyGSLSRVTphosphorylation
unknown		14996911SIGNOR-251092
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CSF1Rphosphorylation
up-regulates
→
CTNND1
PTyr228		phosphorylation
up-regulates
→		CTNND121049007SIGNOR-278928
SRCphosphorylation
up-regulates
→
CTNND1
PTyr228		phosphorylation
up-regulates
→		CTNND111382764SIGNOR-246484
EGFRphosphorylation
up-regulates
→
CTNND1
PTyr228		phosphorylation
down-regulates
⊣		CTNND114996911SIGNOR-251092
Regulator Mechanism/Effect Target SIGNOR-ID
CSF1Rphosphorylation
→
up-regulates quantity by stabilization 		CTNND1SIGNOR-278928
SRCphosphorylation
→
up-regulates activity 		CTNND1SIGNOR-246484
EGFRphosphorylation
→
unknown 		CTNND1SIGNOR-251092