Summary

Name CTNND1
Full Name Catenin delta-1
Synonyms Cadherin-associated Src substrate, CAS, p120 catenin, p120(ctn), p120(cas) | KIAA0384
Primary ID O60716
Links - -
Type protein
Relations 30
Function Key regulator of cell-cell adhesion that associates with and regulates the cell adhesion properties of both C-, E- and N-cadherins, being critical for their surface stability (PubMed:14610055, PubMed:20371349). Beside cell-cell adhesion, regulates gene transcription through several transcription factors including ZBTB33/Kaiso2 and GLIS2, and the activity of Rho family GTPases and downstream cytoskeletal dynamics (PubMed:10207085, PubMed:20371349). Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors (PubMed:17344476).

Viewer

Search Tools

Refine search:

  • by mechanism


  • by effect
  • by organism:


  • by tissue:


  • by cell-line

▶Modifications Tables

Relations


Fatal error: Uncaught TypeError: implode(): Argument #2 ($array) must be of type ?array, string given in /home/prisca/signor/relation_result.php:2084 Stack trace: #0 /home/prisca/signor/relation_result.php(2084): implode() #1 {main} thrown in /home/prisca/signor/relation_result.php on line 2084
Regulator Mechanism target score ℹ
+ GSK3B