Entity Details

Name CLASP2
ID O75122
Role substrate
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
ABL1CLASP2–phosphorylation
up-regulates quantity		24520051SIGNOR-279580
GSK3BCLASP2Ser533QGCSREAsRESSRDTphosphorylation
down-regulates activity		19638411SIGNOR-264825
GSK3BCLASP2Ser537REASRESsRDTSPVRphosphorylation
down-regulates activity		19638411SIGNOR-264826
CDK1CLASP2Ser1234QGYDNSEsSVRKACVphosphorylation
up-regulates activity		23045552SIGNOR-278233
PLK1CLASP2Ser1234QGYDNSEsSVRKACVphosphorylation
up-regulates activity		23045552SIGNOR-278321
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
GSK3Bphosphorylation
up-regulates
→
CLASP2
PSer533		phosphorylation
down-regulates
⊣		CLASP219638411SIGNOR-264825
GSK3Bphosphorylation
up-regulates
→
CLASP2
PSer537		phosphorylation
down-regulates
⊣		CLASP219638411SIGNOR-264826
CDK1phosphorylation
up-regulates
→
CLASP2
PSer1234		phosphorylation
up-regulates
→		CLASP223045552SIGNOR-278233
PLK1phosphorylation
up-regulates
→
CLASP2
PSer1234		phosphorylation
up-regulates
→		CLASP223045552SIGNOR-278321
Regulator Mechanism/Effect Target SIGNOR-ID
ABL1phosphorylation
→
up-regulates quantity 		CLASP2SIGNOR-279580
GSK3Bphosphorylation
→
down-regulates activity 		CLASP2SIGNOR-264825
GSK3Bphosphorylation
→
down-regulates activity 		CLASP2SIGNOR-264826
CDK1phosphorylation
→
up-regulates activity 		CLASP2SIGNOR-278233
PLK1phosphorylation
→
up-regulates activity 		CLASP2SIGNOR-278321