Entity Details

Name ERN1
ID O75460
Role substrate
Enzymatic Domains
Protein kinase 571-832
PROSITE-ProRule
KEN 835-963
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PPM1LERN1–dephosphorylation
up-regulates activity		24327956SIGNOR-277074
MAP3K5ERN1–phosphorylation
up-regulates activity		25249581SIGNOR-279213
ERN1ERN1Tyr628EHPNVIRyFCTEKDRphosphorylation
up-regulates activity		25968568SIGNOR-275417
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
ERN1phosphorylation
up-regulates
→
ERN1
PTyr628		phosphorylation
up-regulates
→		ERN125968568SIGNOR-275417
Regulator Mechanism/Effect Target SIGNOR-ID
PPM1Ldephosphorylation
→
up-regulates activity 		ERN1SIGNOR-277074
MAP3K5phosphorylation
→
up-regulates activity 		ERN1SIGNOR-279213
ERN1phosphorylation
→
up-regulates activity 		ERN1SIGNOR-275417