| Name | NR1I2 |
| ID | O75469 |
| Role | substrate |
| Enzymatic Domains |
NR LBD 146-433 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK2 | NR1I2 | Ser350 | MQAISLFsPDRPGVL | phosphorylation down-regulates quantity by destabilization | 35053380 | SIGNOR-279397 |
| CDK5 | NR1I2 | – | phosphorylation down-regulates activity | 20553580 | SIGNOR-279402 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK2 | phosphorylation up-regulates → | NR1I2 PSer350 | phosphorylation down-regulates ⊣ | NR1I2 | 35053380 | SIGNOR-279397 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CDK2 | phosphorylation down-regulates quantity by destabilization | NR1I2 | SIGNOR-279397 |
| CDK5 | phosphorylation → down-regulates activity | NR1I2 | SIGNOR-279402 |