Entity Details

Name	RPS6KA5_Ser376
ID	O75582
Role	residue
View in

Data Summary

PTM Format

SIGNOR Summary

Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
RPS6KA5	RPS6KA5	Ser376 View in OncoXplorer	EKLFQGYsFVAPSIL	phosphorylation up-regulates activity	15568999	SIGNOR-131391
MAPK1	RPS6KA5	Ser376 View in OncoXplorer	EKLFQGYsFVAPSIL	phosphorylation up-regulates activity	15568999	SIGNOR-249445
MAPK3	RPS6KA5	Ser376 View in OncoXplorer	EKLFQGYsFVAPSIL	phosphorylation up-regulates activity	15568999	SIGNOR-249479
ERK1/2	RPS6KA5	Ser376 View in OncoXplorer	EKLFQGYsFVAPSIL	phosphorylation up-regulates activity	15568999	SIGNOR-249574
MAPK14	RPS6KA5	Ser376 View in OncoXplorer	EKLFQGYsFVAPSIL	phosphorylation up-regulates activity	15568999	SIGNOR-249199

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
RPS6KA5	phosphorylation up-regulates →	RPS6KA5 PSer376	phosphorylation up-regulates →	RPS6KA5	15568999	SIGNOR-131391
MAPK1	phosphorylation up-regulates →	RPS6KA5 PSer376	phosphorylation up-regulates →	RPS6KA5	15568999	SIGNOR-249445
MAPK3	phosphorylation up-regulates →	RPS6KA5 PSer376	phosphorylation up-regulates →	RPS6KA5	15568999	SIGNOR-249479
ERK1/2	phosphorylation up-regulates →	RPS6KA5 PSer376	phosphorylation up-regulates →	RPS6KA5	15568999	SIGNOR-249574
MAPK14	phosphorylation up-regulates →	RPS6KA5 PSer376	phosphorylation up-regulates →	RPS6KA5	15568999	SIGNOR-249199

Regulator	Mechanism/Effect	Target	SIGNOR-ID
RPS6KA5	phosphorylation → up-regulates activity	RPS6KA5	SIGNOR-131391
MAPK1	phosphorylation → up-regulates activity	RPS6KA5	SIGNOR-249445
MAPK3	phosphorylation → up-regulates activity	RPS6KA5	SIGNOR-249479
ERK1/2	phosphorylation → up-regulates activity	RPS6KA5	SIGNOR-249574
MAPK14	phosphorylation → up-regulates activity	RPS6KA5	SIGNOR-249199