| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| LRRK2 | SNAPIN | Thr117 | NHSVAKEtARRRAML | phosphorylation down-regulates | 23949442 | SIGNOR-202436 |
| PRKACA | SNAPIN | Ser50 | HVHAVREsQVELREQ | phosphorylation up-regulates activity | 11283605 | SIGNOR-250053 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| LRRK2 | phosphorylation up-regulates → | SNAPIN PThr117 | phosphorylation down-regulates ⊣ | SNAPIN | 23949442 | SIGNOR-202436 |
| PRKACA | phosphorylation up-regulates → | SNAPIN PSer50 | phosphorylation up-regulates → | SNAPIN | 11283605 | SIGNOR-250053 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| LRRK2 | phosphorylation down-regulates | SNAPIN | SIGNOR-202436 |
| PRKACA | phosphorylation → up-regulates activity | SNAPIN | SIGNOR-250053 |
