| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK14 | NFATC1 | Ser172 | YRDPSCLsPASSLSS | phosphorylation down-regulates | 10652349 | SIGNOR-74560 |
| MAPK3 | NFATC1 | Ser172 | YRDPSCLsPASSLSS | phosphorylation down-regulates | 10652349 | SIGNOR-74564 |
| MAPK10 | NFATC1 | Ser172 | YRDPSCLsPASSLSS | phosphorylation down-regulates | 10652349 | SIGNOR-74556 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK14 | phosphorylation up-regulates → | NFATC1 PSer172 | phosphorylation down-regulates ⊣ | NFATC1 | 10652349 | SIGNOR-74560 |
| MAPK3 | phosphorylation up-regulates → | NFATC1 PSer172 | phosphorylation down-regulates ⊣ | NFATC1 | 10652349 | SIGNOR-74564 |
| MAPK10 | phosphorylation up-regulates → | NFATC1 PSer172 | phosphorylation down-regulates ⊣ | NFATC1 | 10652349 | SIGNOR-74556 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPK14 | phosphorylation![]() down-regulates | NFATC1 | SIGNOR-74560 |
| MAPK3 | phosphorylation![]() down-regulates | NFATC1 | SIGNOR-74564 |
| MAPK10 | phosphorylation![]() down-regulates | NFATC1 | SIGNOR-74556 |