| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCA | NFATC1 | Ser294 | PHGSPRVsVTDDSWL | phosphorylation down-regulates activity | 12351631 | SIGNOR-249175 |
| PRKACA | NFATC1 | Ser294 | PHGSPRVsVTDDSWL | phosphorylation down-regulates | 12351631 | SIGNOR-93539 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCA | phosphorylation up-regulates → | NFATC1 PSer294 | phosphorylation down-regulates ⊣ | NFATC1 | 12351631 | SIGNOR-249175 |
| PRKACA | phosphorylation up-regulates → | NFATC1 PSer294 | phosphorylation down-regulates ⊣ | NFATC1 | 12351631 | SIGNOR-93539 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKCA | phosphorylation → down-regulates activity | NFATC1 | SIGNOR-249175 |
| PRKACA | phosphorylation![]() down-regulates | NFATC1 | SIGNOR-93539 |