Entity Details

Name RPS6KA4_Ser374
ID P01100
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
RPS6KFOSSer374PSSDSLSsPTLLALphosphorylation
up-regulates activity		16055710SIGNOR-262998
RPS6KA1FOSSer374PSSDSLSsPTLLALphosphorylation
up-regulates activity		16055710SIGNOR-262999
RPS6KA4FOSSer374PSSDSLSsPTLLALphosphorylation
up-regulates activity		16055710SIGNOR-263000
MAPK3FOSSer374PSSDSLSsPTLLALphosphorylation
up-regulates activity		12972619SIGNOR-118023
MAPK1FOSSer374PSSDSLSsPTLLALphosphorylation
up-regulates activity		12972619SIGNOR-235671
ERK1/2FOSSer374PSSDSLSsPTLLALphosphorylation
up-regulates activity		12972619SIGNOR-251524
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
RPS6Kphosphorylation
up-regulates
→
FOS
PSer374		phosphorylation
up-regulates
→		FOS16055710SIGNOR-262998
RPS6KA1phosphorylation
up-regulates
→
FOS
PSer374		phosphorylation
up-regulates
→		FOS16055710SIGNOR-262999
RPS6KA4phosphorylation
up-regulates
→
FOS
PSer374		phosphorylation
up-regulates
→		FOS16055710SIGNOR-263000
MAPK3phosphorylation
up-regulates
→
FOS
PSer374		phosphorylation
up-regulates
→		FOS12972619SIGNOR-118023
MAPK1phosphorylation
up-regulates
→
FOS
PSer374		phosphorylation
up-regulates
→		FOS12972619SIGNOR-235671
ERK1/2phosphorylation
up-regulates
→
FOS
PSer374		phosphorylation
up-regulates
→		FOS12972619SIGNOR-251524
Regulator Mechanism/Effect Target SIGNOR-ID
RPS6Kphosphorylation
→
up-regulates activity 		FOSSIGNOR-262998
RPS6KA1phosphorylation
→
up-regulates activity 		FOSSIGNOR-262999
RPS6KA4phosphorylation
→
up-regulates activity 		FOSSIGNOR-263000
MAPK3phosphorylation
→
up-regulates activity 		FOSSIGNOR-118023
MAPK1phosphorylation
→
up-regulates activity 		FOSSIGNOR-235671
ERK1/2phosphorylation
→
up-regulates activity 		FOSSIGNOR-251524