Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
Gbeta	MBP	–		phosphorylation down-regulates	16401070	SIGNOR-270100
PRKACA	MBP	Ser146	RPSQRHGsKYLATAS	phosphorylation unknown	2413024	SIGNOR-250011
PRKCA	MBP	Ser249 View in OncoXplorer	GLSLSRFsWGAEGQR	phosphorylation unknown	2413024	SIGNOR-248872
UHMK1	MBP	Ser299 View in OncoXplorer	GRDSRSGsPMARR	phosphorylation down-regulates	16401070	SIGNOR-143485
PRKACA	MBP	Ser190	RGAPKRGsGKDSHHP	phosphorylation unknown	2413024	SIGNOR-250012
UHMK1	MBP	Ser299 View in OncoXplorer	GRDSRSGsPMARR	phosphorylation down-regulates	10880969	SIGNOR-78895
PRKCA	MBP	Ser141 View in OncoXplorer	MASQKRPsQRHGSKY	phosphorylation unknown	2413024	SIGNOR-248869
PRKCA	MBP	Ser190	RGAPKRGsGKDSHHP	phosphorylation unknown	2413024	SIGNOR-248871
PRKACA	MBP	Ser141 View in OncoXplorer	MASQKRPsQRHGSKY	phosphorylation unknown	2413024	SIGNOR-250010
PRKCA	MBP	Ser266 View in OncoXplorer	FGYGGRAsDYKSAHK	phosphorylation unknown	2413024	SIGNOR-248873
PRKCA	MBP	Ser146	RPSQRHGsKYLATAS	phosphorylation unknown	2413024	SIGNOR-248870
MAPK1	MBP	Thr232 View in OncoXplorer	KNIVTPRtPPPSQGK	phosphorylation down-regulates	16401070	SIGNOR-143477
PRKCA	MBP	Ser285 View in OncoXplorer	VDAQGTLsKIFKLGG	phosphorylation unknown	2413024	SIGNOR-248874
MAPK3	MBP	Thr232 View in OncoXplorer	KNIVTPRtPPPSQGK	phosphorylation down-regulates	16401070	SIGNOR-143481
MAPK3	MBP	Thr232 View in OncoXplorer	KNIVTPRtPPPSQGK	phosphorylation down-regulates	1939237	SIGNOR-22424
PRKACA	MBP	Thr169	FLPRHRDtGILDSIG	phosphorylation unknown	2413024	SIGNOR-250015
ERK1/2	MBP	–		phosphorylation down-regulates	16401070	SIGNOR-270195
PRKCA	MBP	Ser295 View in OncoXplorer	FKLGGRDsRSGSPMA	phosphorylation unknown	2413024	SIGNOR-248875
PRKACA	MBP	Ser266 View in OncoXplorer	FGYGGRAsDYKSAHK	phosphorylation unknown	2413024	SIGNOR-250013
PRKACA	MBP	Ser295 View in OncoXplorer	FKLGGRDsRSGSPMA	phosphorylation unknown	2413024	SIGNOR-250014
MAPK1	MBP	Thr232 View in OncoXplorer	KNIVTPRtPPPSQGK	phosphorylation down-regulates	1939237	SIGNOR-22420
MAPK1	MBP	Thr229 View in OncoXplorer	HFFKNIVtPRTPPPS	phosphorylation unknown	12760422	SIGNOR-249419

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
PRKACA	phosphorylation up-regulates →	MBP PSer146	phosphorylation down-regulates ⊣	MBP	2413024	SIGNOR-250011
PRKCA	phosphorylation up-regulates →	MBP PSer249	phosphorylation down-regulates ⊣	MBP	2413024	SIGNOR-248872
UHMK1	phosphorylation up-regulates →	MBP PSer299	phosphorylation down-regulates ⊣	MBP	16401070	SIGNOR-143485
PRKACA	phosphorylation up-regulates →	MBP PSer190	phosphorylation down-regulates ⊣	MBP	2413024	SIGNOR-250012
UHMK1	phosphorylation up-regulates →	MBP PSer299	phosphorylation down-regulates ⊣	MBP	10880969	SIGNOR-78895
PRKCA	phosphorylation up-regulates →	MBP PSer141	phosphorylation down-regulates ⊣	MBP	2413024	SIGNOR-248869
PRKCA	phosphorylation up-regulates →	MBP PSer190	phosphorylation down-regulates ⊣	MBP	2413024	SIGNOR-248871
PRKACA	phosphorylation up-regulates →	MBP PSer141	phosphorylation down-regulates ⊣	MBP	2413024	SIGNOR-250010
PRKCA	phosphorylation up-regulates →	MBP PSer266	phosphorylation down-regulates ⊣	MBP	2413024	SIGNOR-248873
PRKCA	phosphorylation up-regulates →	MBP PSer146	phosphorylation down-regulates ⊣	MBP	2413024	SIGNOR-248870
MAPK1	phosphorylation up-regulates →	MBP PThr232	phosphorylation down-regulates ⊣	MBP	16401070	SIGNOR-143477
PRKCA	phosphorylation up-regulates →	MBP PSer285	phosphorylation down-regulates ⊣	MBP	2413024	SIGNOR-248874
MAPK3	phosphorylation up-regulates →	MBP PThr232	phosphorylation down-regulates ⊣	MBP	16401070	SIGNOR-143481
MAPK3	phosphorylation up-regulates →	MBP PThr232	phosphorylation down-regulates ⊣	MBP	1939237	SIGNOR-22424
PRKACA	phosphorylation up-regulates →	MBP PThr169	phosphorylation down-regulates ⊣	MBP	2413024	SIGNOR-250015
PRKCA	phosphorylation up-regulates →	MBP PSer295	phosphorylation down-regulates ⊣	MBP	2413024	SIGNOR-248875
PRKACA	phosphorylation up-regulates →	MBP PSer266	phosphorylation down-regulates ⊣	MBP	2413024	SIGNOR-250013
PRKACA	phosphorylation up-regulates →	MBP PSer295	phosphorylation down-regulates ⊣	MBP	2413024	SIGNOR-250014
MAPK1	phosphorylation up-regulates →	MBP PThr232	phosphorylation down-regulates ⊣	MBP	1939237	SIGNOR-22420
MAPK1	phosphorylation up-regulates →	MBP PThr229	phosphorylation down-regulates ⊣	MBP	12760422	SIGNOR-249419

Regulator	Mechanism/Effect	Target	SIGNOR-ID
Gbeta	phosphorylation down-regulates	MBP	SIGNOR-270100
PRKACA	phosphorylation → unknown	MBP	SIGNOR-250011
PRKCA	phosphorylation → unknown	MBP	SIGNOR-248872
UHMK1	phosphorylation down-regulates	MBP	SIGNOR-143485
PRKACA	phosphorylation → unknown	MBP	SIGNOR-250012
UHMK1	phosphorylation down-regulates	MBP	SIGNOR-78895
PRKCA	phosphorylation → unknown	MBP	SIGNOR-248869
PRKCA	phosphorylation → unknown	MBP	SIGNOR-248871
PRKACA	phosphorylation → unknown	MBP	SIGNOR-250010
PRKCA	phosphorylation → unknown	MBP	SIGNOR-248873
PRKCA	phosphorylation → unknown	MBP	SIGNOR-248870
MAPK1	phosphorylation down-regulates	MBP	SIGNOR-143477
PRKCA	phosphorylation → unknown	MBP	SIGNOR-248874
MAPK3	phosphorylation down-regulates	MBP	SIGNOR-143481
MAPK3	phosphorylation down-regulates	MBP	SIGNOR-22424
PRKACA	phosphorylation → unknown	MBP	SIGNOR-250015
ERK1/2	phosphorylation down-regulates	MBP	SIGNOR-270195
PRKCA	phosphorylation → unknown	MBP	SIGNOR-248875
PRKACA	phosphorylation → unknown	MBP	SIGNOR-250013
PRKACA	phosphorylation → unknown	MBP	SIGNOR-250014
MAPK1	phosphorylation down-regulates	MBP	SIGNOR-22420
MAPK1	phosphorylation → unknown	MBP	SIGNOR-249419