| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK1 | MBP | Thr232 | KNIVTPRtPPPSQGK | phosphorylation down-regulates | 16401070 | SIGNOR-143477 |
| MAPK3 | MBP | Thr232 | KNIVTPRtPPPSQGK | phosphorylation down-regulates | 1939237 | SIGNOR-22424 |
| MAPK1 | MBP | Thr232 | KNIVTPRtPPPSQGK | phosphorylation down-regulates | 1939237 | SIGNOR-22420 |
| MAPK3 | MBP | Thr232 | KNIVTPRtPPPSQGK | phosphorylation down-regulates | 16401070 | SIGNOR-143481 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK1 | phosphorylation up-regulates → | MBP PThr232 | phosphorylation down-regulates ⊣ | MBP | 16401070 | SIGNOR-143477 |
| MAPK3 | phosphorylation up-regulates → | MBP PThr232 | phosphorylation down-regulates ⊣ | MBP | 1939237 | SIGNOR-22424 |
| MAPK1 | phosphorylation up-regulates → | MBP PThr232 | phosphorylation down-regulates ⊣ | MBP | 1939237 | SIGNOR-22420 |
| MAPK3 | phosphorylation up-regulates → | MBP PThr232 | phosphorylation down-regulates ⊣ | MBP | 16401070 | SIGNOR-143481 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPK1 | phosphorylation down-regulates | MBP | SIGNOR-143477 |
| MAPK3 | phosphorylation down-regulates | MBP | SIGNOR-22424 |
| MAPK1 | phosphorylation down-regulates | MBP | SIGNOR-22420 |
| MAPK3 | phosphorylation down-regulates | MBP | SIGNOR-143481 |
