| Name | HMGCR |
| ID | P04035 |
| Role | substrate |
| Enzymatic Domains |
SSD 61-218 PROSITE-ProRule |
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|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKACA | HMGCR | Ser872 | SHMIHNRsKINLQDL | phosphorylation down-regulates activity | 2369897 | SIGNOR-249992 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKACA | phosphorylation up-regulates → | HMGCR PSer872 | phosphorylation down-regulates ⊣ | HMGCR | 2369897 | SIGNOR-249992 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKACA | phosphorylation → down-regulates activity | HMGCR | SIGNOR-249992 |