| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SRC | RAF1 | Tyr340 | RGQRDSSyYWEIEAS | phosphorylation up-regulates | 10998357 | SIGNOR-82150 |
| SRC | RAF1 | Tyr340 | RGQRDSSyYWEIEAS | phosphorylation up-regulates | 12551923 | SIGNOR-97635 |
| JAK2 | RAF1 | Tyr340 | RGQRDSSyYWEIEAS | phosphorylation up-regulates activity | 8876196 | SIGNOR-251361 |
| SRC | RAF1 | Tyr340 | RGQRDSSyYWEIEAS | phosphorylation up-regulates | 7692235 | SIGNOR-32081 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SRC | phosphorylation up-regulates → | RAF1 PTyr340 | phosphorylation up-regulates → | RAF1 | 10998357 | SIGNOR-82150 |
| SRC | phosphorylation up-regulates → | RAF1 PTyr340 | phosphorylation up-regulates → | RAF1 | 12551923 | SIGNOR-97635 |
| JAK2 | phosphorylation up-regulates → | RAF1 PTyr340 | phosphorylation up-regulates → | RAF1 | 8876196 | SIGNOR-251361 |
| SRC | phosphorylation up-regulates → | RAF1 PTyr340 | phosphorylation up-regulates → | RAF1 | 7692235 | SIGNOR-32081 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| SRC | phosphorylation → up-regulates | RAF1 | SIGNOR-82150 |
| SRC | phosphorylation → up-regulates | RAF1 | SIGNOR-97635 |
| JAK2 | phosphorylation → up-regulates activity | RAF1 | SIGNOR-251361 |
| SRC | phosphorylation → up-regulates | RAF1 | SIGNOR-32081 |
