Entity Details

Name JAK2_Tyr341
ID P04049
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
SRCRAF1Tyr341GQRDSSYyWEIEASEphosphorylation
up-regulates		12551923SIGNOR-97639
JAK2RAF1Tyr341GQRDSSYyWEIEASEphosphorylation
up-regulates activity		8876196SIGNOR-251362
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
SRCphosphorylation
up-regulates
→
RAF1
PTyr341		phosphorylation
up-regulates
→		RAF112551923SIGNOR-97639
JAK2phosphorylation
up-regulates
→
RAF1
PTyr341		phosphorylation
up-regulates
→		RAF18876196SIGNOR-251362
Regulator Mechanism/Effect Target SIGNOR-ID
SRCphosphorylation
→
up-regulates 		RAF1SIGNOR-97639
JAK2phosphorylation
→
up-regulates activity 		RAF1SIGNOR-251362