Entity Details

Name MAPK3_Ser301
ID P04049
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
MAPK1RAF1Ser301SSSPNNLsPTGWSQPphosphorylation
down-regulates activity		15664191SIGNOR-249443
MAPK3RAF1Ser301SSSPNNLsPTGWSQPphosphorylation
down-regulates		16407412SIGNOR-143696
ERK1/2RAF1Ser301SSSPNNLsPTGWSQPphosphorylation
down-regulates		16407412SIGNOR-244685
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
MAPK1phosphorylation
up-regulates
→
RAF1
PSer301		phosphorylation
down-regulates
⊣		RAF115664191SIGNOR-249443
MAPK3phosphorylation
up-regulates
→
RAF1
PSer301		phosphorylation
down-regulates
⊣		RAF116407412SIGNOR-143696
ERK1/2phosphorylation
up-regulates
→
RAF1
PSer301		phosphorylation
down-regulates
⊣		RAF116407412SIGNOR-244685
Regulator Mechanism/Effect Target SIGNOR-ID
MAPK1phosphorylation
→
down-regulates activity 		RAF1SIGNOR-249443
MAPK3phosphorylation
img/direct_inhibition.png
down-regulates 		RAF1SIGNOR-143696
ERK1/2phosphorylation
img/direct_inhibition.png
down-regulates 		RAF1SIGNOR-244685