| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKACA | RAF1 | Ser233 | VSSQHRYsTPHAFTF | phosphorylation down-regulates activity | 12801936 | SIGNOR-250040 |
| PRKCA | RAF1 | Ser233 | VSSQHRYsTPHAFTF | phosphorylation unknown | 12551925 | SIGNOR-37466 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKACA | phosphorylation up-regulates → | RAF1 PSer233 | phosphorylation down-regulates ⊣ | RAF1 | 12801936 | SIGNOR-250040 |
| PRKCA | phosphorylation up-regulates → | RAF1 PSer233 | phosphorylation down-regulates ⊣ | RAF1 | 12551925 | SIGNOR-37466 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKACA | phosphorylation → down-regulates activity | RAF1 | SIGNOR-250040 |
| PRKCA | phosphorylation → unknown | RAF1 | SIGNOR-37466 |
