Entity Details

Name CDK7_Ser376
ID P04637
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CAK complexTP53Ser376LKSKKGQsTSRHKKLphosphorylation
up-regulates		9315650SIGNOR-269328
CDK7TP53Ser376LKSKKGQsTSRHKKLphosphorylation
up-regulates		9315650SIGNOR-51284
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CAK complexphosphorylation
up-regulates
→
TP53
PSer376		phosphorylation
up-regulates
→		TP539315650SIGNOR-269328
CDK7phosphorylation
up-regulates
→
TP53
PSer376		phosphorylation
up-regulates
→		TP539315650SIGNOR-51284
Regulator Mechanism/Effect Target SIGNOR-ID
CAK complexphosphorylation
→
up-regulates 		TP53SIGNOR-269328
CDK7phosphorylation
→
up-regulates 		TP53SIGNOR-51284