Entity Details

Name CHEK1_Ser366
ID P04637
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CHEK2TP53Ser366PGGSRAHsSHLKSKKphosphorylation
up-regulates quantity by stabilization		10673501SIGNOR-75013
CHEK1TP53Ser366PGGSRAHsSHLKSKKphosphorylation
up-regulates activity		15659650SIGNOR-217853
CHEK2TP53Ser366PGGSRAHsSHLKSKKphosphorylation
up-regulates quantity by stabilization		15659650SIGNOR-75633
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CHEK2phosphorylation
up-regulates
→
TP53
PSer366		phosphorylation
up-regulates
→		TP5310673501SIGNOR-75013
CHEK1phosphorylation
up-regulates
→
TP53
PSer366		phosphorylation
up-regulates
→		TP5315659650SIGNOR-217853
CHEK2phosphorylation
up-regulates
→
TP53
PSer366		phosphorylation
up-regulates
→		TP5315659650SIGNOR-75633
Regulator Mechanism/Effect Target SIGNOR-ID
CHEK2phosphorylation
→
up-regulates quantity by stabilization 		TP53SIGNOR-75013
CHEK1phosphorylation
→
up-regulates activity 		TP53SIGNOR-217853
CHEK2phosphorylation
→
up-regulates quantity by stabilization 		TP53SIGNOR-75633