Entity Details

Name PPP2CA_Thr55
ID P04637
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PPP2CBTP53Thr55DDIEQWFtEDPGPDEdephosphorylation
up-regulates quantity by stabilization		17245430SIGNOR-248583
TAF1TP53Thr55DDIEQWFtEDPGPDEphosphorylation
down-regulates		15053879SIGNOR-123651
GRK5TP53Thr55DDIEQWFtEDPGPDEphosphorylation
down-regulates		20124405SIGNOR-163707
PPP2CATP53Thr55DDIEQWFtEDPGPDEdephosphorylation
up-regulates quantity by stabilization		17245430SIGNOR-248618
MAPK1TP53Thr55DDIEQWFtEDPGPDEphosphorylation
up-regulates activity		15116093SIGNOR-279068
PPP2R5CTP53Thr55DDIEQWFtEDPGPDEdephosphorylation
up-regulates quantity by stabilization		17245430SIGNOR-268154
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PPP2CBdephosphorylation
down-regulates
⊣
TP53
PThr55		dephosphorylation
down-regulates
⊣		TP5317245430SIGNOR-248583
TAF1phosphorylation
up-regulates
→
TP53
PThr55		phosphorylation
down-regulates
⊣		TP5315053879SIGNOR-123651
GRK5phosphorylation
up-regulates
→
TP53
PThr55		phosphorylation
down-regulates
⊣		TP5320124405SIGNOR-163707
PPP2CAdephosphorylation
down-regulates
⊣
TP53
PThr55		dephosphorylation
down-regulates
⊣		TP5317245430SIGNOR-248618
MAPK1phosphorylation
up-regulates
→
TP53
PThr55		phosphorylation
up-regulates
→		TP5315116093SIGNOR-279068
PPP2R5Cdephosphorylation
down-regulates
⊣
TP53
PThr55		dephosphorylation
down-regulates
⊣		TP5317245430SIGNOR-268154
Regulator Mechanism/Effect Target SIGNOR-ID
PPP2CBdephosphorylation
→
up-regulates quantity by stabilization 		TP53SIGNOR-248583
TAF1phosphorylation
img/direct_inhibition.png
down-regulates 		TP53SIGNOR-123651
GRK5phosphorylation
img/direct_inhibition.png
down-regulates 		TP53SIGNOR-163707
PPP2CAdephosphorylation
→
up-regulates quantity by stabilization 		TP53SIGNOR-248618
MAPK1phosphorylation
→
up-regulates activity 		TP53SIGNOR-279068
PPP2R5Cdephosphorylation
→
up-regulates quantity by stabilization 		TP53SIGNOR-268154