Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
PRKCH	ITGB2	Thr758 View in OncoXplorer	NPLFKSAtTTVMNPK	phosphorylation unknown	11700305	SIGNOR-249123
PRKCD	ITGB2	Thr758 View in OncoXplorer	NPLFKSAtTTVMNPK	phosphorylation up-regulates activity	11700305	SIGNOR-111495
PRKCD	ITGB2	Thr758 View in OncoXplorer	NPLFKSAtTTVMNPK	phosphorylation up-regulates	18550856	SIGNOR-178897
PRKCA	ITGB2	Thr758 View in OncoXplorer	NPLFKSAtTTVMNPK	phosphorylation unknown	11700305	SIGNOR-249121
PRKCB	ITGB2	Thr758 View in OncoXplorer	NPLFKSAtTTVMNPK	phosphorylation unknown	11700305	SIGNOR-249122
PRKCD	ITGB2	Thr758 View in OncoXplorer	NPLFKSAtTTVMNPK	phosphorylation unknown	11700305	SIGNOR-249124

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
PRKCH	phosphorylation up-regulates →	ITGB2 PThr758	phosphorylation down-regulates ⊣	ITGB2	11700305	SIGNOR-249123
PRKCD	phosphorylation up-regulates →	ITGB2 PThr758	phosphorylation up-regulates →	ITGB2	11700305	SIGNOR-111495
PRKCD	phosphorylation up-regulates →	ITGB2 PThr758	phosphorylation up-regulates →	ITGB2	18550856	SIGNOR-178897
PRKCA	phosphorylation up-regulates →	ITGB2 PThr758	phosphorylation down-regulates ⊣	ITGB2	11700305	SIGNOR-249121
PRKCB	phosphorylation up-regulates →	ITGB2 PThr758	phosphorylation down-regulates ⊣	ITGB2	11700305	SIGNOR-249122
PRKCD	phosphorylation up-regulates →	ITGB2 PThr758	phosphorylation down-regulates ⊣	ITGB2	11700305	SIGNOR-249124

Regulator	Mechanism/Effect	Target	SIGNOR-ID
PRKCH	phosphorylation → unknown	ITGB2	SIGNOR-249123
PRKCD	phosphorylation → up-regulates activity	ITGB2	SIGNOR-111495
PRKCD	phosphorylation → up-regulates	ITGB2	SIGNOR-178897
PRKCA	phosphorylation → unknown	ITGB2	SIGNOR-249121
PRKCB	phosphorylation → unknown	ITGB2	SIGNOR-249122
PRKCD	phosphorylation → unknown	ITGB2	SIGNOR-249124