| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCB | ITGB2 | Ser745 | FEKEKLKsQWNNDNP | phosphorylation unknown | 11700305 | SIGNOR-249119 |
| PRKCH | ITGB2 | Ser745 | FEKEKLKsQWNNDNP | phosphorylation unknown | 11700305 | SIGNOR-249118 |
| PRKCD | ITGB2 | Ser745 | FEKEKLKsQWNNDNP | phosphorylation unknown | 11700305 | SIGNOR-249120 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCB | phosphorylation up-regulates → | ITGB2 PSer745 | phosphorylation down-regulates ⊣ | ITGB2 | 11700305 | SIGNOR-249119 |
| PRKCH | phosphorylation up-regulates → | ITGB2 PSer745 | phosphorylation down-regulates ⊣ | ITGB2 | 11700305 | SIGNOR-249118 |
| PRKCD | phosphorylation up-regulates → | ITGB2 PSer745 | phosphorylation down-regulates ⊣ | ITGB2 | 11700305 | SIGNOR-249120 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKCB | phosphorylation → unknown | ITGB2 | SIGNOR-249119 |
| PRKCH | phosphorylation → unknown | ITGB2 | SIGNOR-249118 |
| PRKCD | phosphorylation → unknown | ITGB2 | SIGNOR-249120 |
