| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSNK2A1 | HMGN1 | Ser99 | AGEKEAKsD | phosphorylation down-regulates | 10739259 | SIGNOR-76278 |
| CSNK2A1 | HMGN1 | Ser89 | KTEESPAsDEAGEKE | phosphorylation down-regulates | 10739259 | SIGNOR-76274 |
| PRKCA | HMGN1 | Ser21 | KEEPKRRsARLSAKP | phosphorylation down-regulates | 10739259 | SIGNOR-76282 |
| PRKACA | HMGN1 | Ser7 | sSAEGAAK | phosphorylation down-regulates activity | 11438671 | SIGNOR-249993 |
| RPS6KA3 | HMGN1 | Ser7 | sSAEGAAK | phosphorylation unknown | 12773393 | SIGNOR-249215 |
| CSNK2A1 | HMGN1 | Ser8 | MPKRKVSsAEGAAKE | phosphorylation down-regulates | 10739259 | SIGNOR-76270 |
| RPS6KA4 | HMGN1 | Ser7 | sSAEGAAK | phosphorylation unknown | 12773393 | SIGNOR-249216 |
| RPS6KA3 | HMGN1 | Ser21 | KEEPKRRsARLSAKP | phosphorylation down-regulates activity | 11438671 | SIGNOR-249100 |
| RPS6KA5 | HMGN1 | Ser7 | sSAEGAAK | phosphorylation down-regulates activity | 12213813 | SIGNOR-262988 |
| RPS6KA3 | HMGN1 | Ser25 | KRRSARLsAKPPAKV | phosphorylation down-regulates activity | 11438671 | SIGNOR-249101 |
| CSNK2A1 | HMGN1 | Ser7 | sSAEGAAK | phosphorylation down-regulates | 10739259 | SIGNOR-76266 |
| PRKCA | HMGN1 | Ser25 | KRRSARLsAKPPAKV | phosphorylation down-regulates | 10739259 | SIGNOR-76286 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CSNK2A1 | phosphorylation up-regulates → | HMGN1 PSer99 | phosphorylation down-regulates ⊣ | HMGN1 | 10739259 | SIGNOR-76278 |
| CSNK2A1 | phosphorylation up-regulates → | HMGN1 PSer89 | phosphorylation down-regulates ⊣ | HMGN1 | 10739259 | SIGNOR-76274 |
| PRKCA | phosphorylation up-regulates → | HMGN1 PSer21 | phosphorylation down-regulates ⊣ | HMGN1 | 10739259 | SIGNOR-76282 |
| PRKACA | phosphorylation up-regulates → | HMGN1 PSer7 | phosphorylation down-regulates ⊣ | HMGN1 | 11438671 | SIGNOR-249993 |
| RPS6KA3 | phosphorylation up-regulates → | HMGN1 PSer7 | phosphorylation down-regulates ⊣ | HMGN1 | 12773393 | SIGNOR-249215 |
| CSNK2A1 | phosphorylation up-regulates → | HMGN1 PSer8 | phosphorylation down-regulates ⊣ | HMGN1 | 10739259 | SIGNOR-76270 |
| RPS6KA4 | phosphorylation up-regulates → | HMGN1 PSer7 | phosphorylation down-regulates ⊣ | HMGN1 | 12773393 | SIGNOR-249216 |
| RPS6KA3 | phosphorylation up-regulates → | HMGN1 PSer21 | phosphorylation down-regulates ⊣ | HMGN1 | 11438671 | SIGNOR-249100 |
| RPS6KA5 | phosphorylation up-regulates → | HMGN1 PSer7 | phosphorylation down-regulates ⊣ | HMGN1 | 12213813 | SIGNOR-262988 |
| RPS6KA3 | phosphorylation up-regulates → | HMGN1 PSer25 | phosphorylation down-regulates ⊣ | HMGN1 | 11438671 | SIGNOR-249101 |
| CSNK2A1 | phosphorylation up-regulates → | HMGN1 PSer7 | phosphorylation down-regulates ⊣ | HMGN1 | 10739259 | SIGNOR-76266 |
| PRKCA | phosphorylation up-regulates → | HMGN1 PSer25 | phosphorylation down-regulates ⊣ | HMGN1 | 10739259 | SIGNOR-76286 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CSNK2A1 | phosphorylation down-regulates | HMGN1 | SIGNOR-76278 |
| CSNK2A1 | phosphorylation down-regulates | HMGN1 | SIGNOR-76274 |
| PRKCA | phosphorylation down-regulates | HMGN1 | SIGNOR-76282 |
| PRKACA | phosphorylation → down-regulates activity | HMGN1 | SIGNOR-249993 |
| RPS6KA3 | phosphorylation → unknown | HMGN1 | SIGNOR-249215 |
| CSNK2A1 | phosphorylation down-regulates | HMGN1 | SIGNOR-76270 |
| RPS6KA4 | phosphorylation → unknown | HMGN1 | SIGNOR-249216 |
| RPS6KA3 | phosphorylation → down-regulates activity | HMGN1 | SIGNOR-249100 |
| RPS6KA5 | phosphorylation → down-regulates activity | HMGN1 | SIGNOR-262988 |
| RPS6KA3 | phosphorylation → down-regulates activity | HMGN1 | SIGNOR-249101 |
| CSNK2A1 | phosphorylation down-regulates | HMGN1 | SIGNOR-76266 |
| PRKCA | phosphorylation down-regulates | HMGN1 | SIGNOR-76286 |
