Summary

Name HMGN1
Full Name Non-histone chromosomal protein HMG-14
Synonyms High mobility group nucleosome-binding domain-containing protein 1 | HMG14
Primary ID P05114
Links - -
Type protein
Relations 11
Function Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation. Inhibits the phosphorylation of nucleosomal histones H3 and H2A by RPS6KA5/MSK1 and RPS6KA3/RSK2 (By similarity).

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Modifications Tables

Relations

Regulator Mechanism target score
+ down-regulates activity img/direct_inhibition.png phosphorylation HMGN1 0.14
Publications: 2 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation HMGN1 0.14
Publications: 2 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation HMGN1 0.14
Publications: 4 Organism: Homo Sapiens
+ img/unknown.png phosphorylation HMGN1 0.14
Publications: 1 Organism: Mus Musculus
+ img/unknown.png phosphorylation HMGN1 0.28
Publications: 1 Organism: Mus Musculus
+ down-regulates activity img/direct_inhibition.png phosphorylation HMGN1 0.14
Publications: 1 Organism: Homo Sapiens