| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCA | HMGN1 | Ser21 | KEEPKRRsARLSAKP | phosphorylation down-regulates | 10739259 | SIGNOR-76282 |
| RPS6KA3 | HMGN1 | Ser21 | KEEPKRRsARLSAKP | phosphorylation down-regulates activity | 11438671 | SIGNOR-249100 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCA | phosphorylation up-regulates → | HMGN1 PSer21 | phosphorylation down-regulates ⊣ | HMGN1 | 10739259 | SIGNOR-76282 |
| RPS6KA3 | phosphorylation up-regulates → | HMGN1 PSer21 | phosphorylation down-regulates ⊣ | HMGN1 | 11438671 | SIGNOR-249100 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKCA | phosphorylation down-regulates | HMGN1 | SIGNOR-76282 |
| RPS6KA3 | phosphorylation → down-regulates activity | HMGN1 | SIGNOR-249100 |
