| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| EIF2AK1 | EIF2S1 | Ser49 | IEGMILLsELSRRRI | phosphorylation up-regulates | 10563826 | SIGNOR-72152 |
| EIF2AK1 | EIF2S1 | Ser49 | IEGMILLsELSRRRI | phosphorylation up-regulates | 3352609 | SIGNOR-24539 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| EIF2AK1 | phosphorylation up-regulates → | EIF2S1 PSer49 | phosphorylation up-regulates → | EIF2S1 | 10563826 | SIGNOR-72152 |
| EIF2AK1 | phosphorylation up-regulates → | EIF2S1 PSer49 | phosphorylation up-regulates → | EIF2S1 | 3352609 | SIGNOR-24539 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| EIF2AK1 | phosphorylation → up-regulates | EIF2S1 | SIGNOR-72152 |
| EIF2AK1 | phosphorylation → up-regulates | EIF2S1 | SIGNOR-24539 |
