| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPP1CA | EIF2S1 | Ser51 | S-->L | dephosphorylation down-regulates activity | 11381086 | SIGNOR-281567 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPP1CA | dephosphorylation down-regulates ⊣ | EIF2S1 PSer51 | dephosphorylation up-regulates → | EIF2S1 | 11381086 | SIGNOR-281567 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PPP1CA | dephosphorylation → down-regulates activity | EIF2S1 | SIGNOR-281567 |