| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTPRA | FYN | Tyr531 | FTATEPQyQPGENL | dephosphorylation up-regulates activity | 9535845 | SIGNOR-248435 |
| PTPRC | FYN | Tyr531 | FTATEPQyQPGENL | dephosphorylation up-regulates activity | 11909961 | SIGNOR-248352 |
| PTPRF | FYN | Tyr531 | FTATEPQyQPGENL | dephosphorylation up-regulates | 12496362 | SIGNOR-96764 |
| PTPRA | FYN | Tyr531 | FTATEPQyQPGENL | dephosphorylation up-regulates | 17507376 | SIGNOR-154796 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTPRA | dephosphorylation down-regulates ⊣ | FYN PTyr531 | dephosphorylation down-regulates ⊣ | FYN | 9535845 | SIGNOR-248435 |
| PTPRC | dephosphorylation down-regulates ⊣ | FYN PTyr531 | dephosphorylation down-regulates ⊣ | FYN | 11909961 | SIGNOR-248352 |
| PTPRF | dephosphorylation down-regulates ⊣ | FYN PTyr531 | dephosphorylation down-regulates ⊣ | FYN | 12496362 | SIGNOR-96764 |
| PTPRA | dephosphorylation down-regulates ⊣ | FYN PTyr531 | dephosphorylation down-regulates ⊣ | FYN | 17507376 | SIGNOR-154796 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PTPRA | dephosphorylation → up-regulates activity | FYN | SIGNOR-248435 |
| PTPRC | dephosphorylation → up-regulates activity | FYN | SIGNOR-248352 |
| PTPRF | dephosphorylation → up-regulates | FYN | SIGNOR-96764 |
| PTPRA | dephosphorylation → up-regulates | FYN | SIGNOR-154796 |
