| Name | PGR |
| ID | P06401 |
| Role | substrate |
| Enzymatic Domains |
NR LBD 679-913 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK1 | PGR | Ser294 | APMAPGRsPLATTVM | phosphorylation down-regulates | 10655479 | SIGNOR-74712 |
| CDK2 | PGR | Thr430 | PPLPPRAtPSRPGEA | phosphorylation unknown | 11110801 | SIGNOR-85000 |
| CDK2 | PGR | Ser20 | HVAGGPPsPEVGSPL | phosphorylation unknown | 11110801 | SIGNOR-84980 |
| CSNK2A1 | PGR | Ser81 | TQDQQSLsDVEGAYS | phosphorylation unknown | 7983041 | SIGNOR-250926 |
| CDK2 | PGR | Ser213 | SGAPVKPsPQAAAVE | phosphorylation unknown | 11110801 | SIGNOR-84984 |
| GSK3B | PGR | Ser554 | PDSEASQsPQYSFES | phosphorylation down-regulates quantity by destabilization | 23880761 | SIGNOR-276498 |
| Gbeta | PGR | – | phosphorylation down-regulates | 10655479 | SIGNOR-270040 | |
| ERK1/2 | PGR | – | phosphorylation down-regulates | 10655479 | SIGNOR-270157 | |
| CDK2 | PGR | Ser294 | APMAPGRsPLATTVM | phosphorylation down-regulates | 10655479 | SIGNOR-74708 |
| CDK2 | PGR | Ser554 | PDSEASQsPQYSFES | phosphorylation unknown | 11110801 | SIGNOR-84992 |
| CDK2 | PGR | Ser25 | PPSPEVGsPLLCRPA | phosphorylation unknown | 11110801 | SIGNOR-84988 |
| CDK2 | PGR | Ser676 | LSQRFTFsPGQDIQL | phosphorylation unknown | 11110801 | SIGNOR-84996 |
| MAPK3 | PGR | Ser294 | APMAPGRsPLATTVM | phosphorylation down-regulates | 10655479 | SIGNOR-74716 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK1 | phosphorylation up-regulates → | PGR PSer294 | phosphorylation down-regulates ⊣ | PGR | 10655479 | SIGNOR-74712 |
| CDK2 | phosphorylation up-regulates → | PGR PThr430 | phosphorylation down-regulates ⊣ | PGR | 11110801 | SIGNOR-85000 |
| CDK2 | phosphorylation up-regulates → | PGR PSer20 | phosphorylation down-regulates ⊣ | PGR | 11110801 | SIGNOR-84980 |
| CSNK2A1 | phosphorylation up-regulates → | PGR PSer81 | phosphorylation down-regulates ⊣ | PGR | 7983041 | SIGNOR-250926 |
| CDK2 | phosphorylation up-regulates → | PGR PSer213 | phosphorylation down-regulates ⊣ | PGR | 11110801 | SIGNOR-84984 |
| GSK3B | phosphorylation up-regulates → | PGR PSer554 | phosphorylation down-regulates ⊣ | PGR | 23880761 | SIGNOR-276498 |
| CDK2 | phosphorylation up-regulates → | PGR PSer294 | phosphorylation down-regulates ⊣ | PGR | 10655479 | SIGNOR-74708 |
| CDK2 | phosphorylation up-regulates → | PGR PSer554 | phosphorylation down-regulates ⊣ | PGR | 11110801 | SIGNOR-84992 |
| CDK2 | phosphorylation up-regulates → | PGR PSer25 | phosphorylation down-regulates ⊣ | PGR | 11110801 | SIGNOR-84988 |
| CDK2 | phosphorylation up-regulates → | PGR PSer676 | phosphorylation down-regulates ⊣ | PGR | 11110801 | SIGNOR-84996 |
| MAPK3 | phosphorylation up-regulates → | PGR PSer294 | phosphorylation down-regulates ⊣ | PGR | 10655479 | SIGNOR-74716 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPK1 | phosphorylation down-regulates | PGR | SIGNOR-74712 |
| CDK2 | phosphorylation → unknown | PGR | SIGNOR-85000 |
| CDK2 | phosphorylation → unknown | PGR | SIGNOR-84980 |
| CSNK2A1 | phosphorylation → unknown | PGR | SIGNOR-250926 |
| CDK2 | phosphorylation → unknown | PGR | SIGNOR-84984 |
| GSK3B | phosphorylation down-regulates quantity by destabilization | PGR | SIGNOR-276498 |
| Gbeta | phosphorylation down-regulates | PGR | SIGNOR-270040 |
| ERK1/2 | phosphorylation down-regulates | PGR | SIGNOR-270157 |
| CDK2 | phosphorylation down-regulates | PGR | SIGNOR-74708 |
| CDK2 | phosphorylation → unknown | PGR | SIGNOR-84992 |
| CDK2 | phosphorylation → unknown | PGR | SIGNOR-84988 |
| CDK2 | phosphorylation → unknown | PGR | SIGNOR-84996 |
| MAPK3 | phosphorylation down-regulates | PGR | SIGNOR-74716 |