Summary

Name PGR
Full Name Progesterone receptor
Synonyms PR, Nuclear receptor subfamily 3 group C member 3 | NR3C3
Primary ID P06401
Links - -
Type protein
Relations 16
Function The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Depending on the isoform, progesterone receptor functions as transcriptional activator or repressor.

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Modifications Tables

Relations

Regulator Mechanism target score
+ img/unknown.png phosphorylation PGR 0.14
Publications: 6 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation PGR 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation PGR 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation PGR 0.14
Publications: 1 Organism: Homo Sapiens
+ img/unknown.png phosphorylation PGR 0.14
Publications: 1 Organism: In Vitro
+ up-regulates img/indirect-activation.png PGR 0.31
Publications: 1 Organism: Homo Sapiens
+ down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation PGR 0.28
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding ESR1 0.3
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png acetylation PGR 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png chemical activation PGR 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation KLK4 0.14
Publications: 1 Organism: Homo Sapiens