| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GSK3B | PGR | Ser554 | PDSEASQsPQYSFES | phosphorylation down-regulates quantity by destabilization | 23880761 | SIGNOR-276498 |
| CDK2 | PGR | Ser554 | PDSEASQsPQYSFES | phosphorylation unknown | 11110801 | SIGNOR-84992 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GSK3B | phosphorylation up-regulates → | PGR PSer554 | phosphorylation down-regulates ⊣ | PGR | 23880761 | SIGNOR-276498 |
| CDK2 | phosphorylation up-regulates → | PGR PSer554 | phosphorylation down-regulates ⊣ | PGR | 11110801 | SIGNOR-84992 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| GSK3B | phosphorylation![]() down-regulates quantity by destabilization | PGR | SIGNOR-276498 |
| CDK2 | phosphorylation → unknown | PGR | SIGNOR-84992 |