| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK3 | SP1 | Thr453 | SGPIIIRtPTVGPNG | phosphorylation up-regulates | 14744793 | SIGNOR-248062 |
| MAPK3 | SP1 | Thr453 | SGPIIIRtPTVGPNG | phosphorylation up-regulates activity | 14744793 | SIGNOR-249480 |
| MAPK3 | SP1 | Thr453 | SGPIIIRtPTVGPNG | phosphorylation up-regulates | 14593115 | SIGNOR-248066 |
| MAPK1 | SP1 | Thr453 | SGPIIIRtPTVGPNG | phosphorylation up-regulates | 11904305 | SIGNOR-116162 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK3 | phosphorylation up-regulates → | SP1 PThr453 | phosphorylation up-regulates → | SP1 | 14744793 | SIGNOR-248062 |
| MAPK3 | phosphorylation up-regulates → | SP1 PThr453 | phosphorylation up-regulates → | SP1 | 14744793 | SIGNOR-249480 |
| MAPK3 | phosphorylation up-regulates → | SP1 PThr453 | phosphorylation up-regulates → | SP1 | 14593115 | SIGNOR-248066 |
| MAPK1 | phosphorylation up-regulates → | SP1 PThr453 | phosphorylation up-regulates → | SP1 | 11904305 | SIGNOR-116162 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPK3 | phosphorylation → up-regulates | SP1 | SIGNOR-248062 |
| MAPK3 | phosphorylation → up-regulates activity | SP1 | SIGNOR-249480 |
| MAPK3 | phosphorylation → up-regulates | SP1 | SIGNOR-248066 |
| MAPK1 | phosphorylation → up-regulates | SP1 | SIGNOR-116162 |
