Entity Details

Name AMPK_Ser102
ID P08151
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
MAPK1GLI1Ser102LQTVIRTsPSSLVAFphosphorylation
up-regulates activity		35831023SIGNOR-277601
PRKAA1GLI1Ser102LQTVIRTsPSSLVAFphosphorylation
down-regulates activity		26190112SIGNOR-259861
AMPKGLI1Ser102LQTVIRTsPSSLVAFphosphorylation
down-regulates quantity by destabilization		26190112SIGNOR-253542
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
MAPK1phosphorylation
up-regulates
→
GLI1
PSer102		phosphorylation
up-regulates
→		GLI135831023SIGNOR-277601
PRKAA1phosphorylation
up-regulates
→
GLI1
PSer102		phosphorylation
down-regulates
⊣		GLI126190112SIGNOR-259861
AMPKphosphorylation
up-regulates
→
GLI1
PSer102		phosphorylation
down-regulates
⊣		GLI126190112SIGNOR-253542
Regulator Mechanism/Effect Target SIGNOR-ID
MAPK1phosphorylation
→
up-regulates activity 		GLI1SIGNOR-277601
PRKAA1phosphorylation
→
down-regulates activity 		GLI1SIGNOR-259861
AMPKphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		GLI1SIGNOR-253542