| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PKA | GLI1 | Thr374 | PGCTKRYtDPSSLRK | phosphorylation down-regulates activity | 16293631 | SIGNOR-276044 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PKA | phosphorylation up-regulates → | GLI1 PThr374 | phosphorylation down-regulates ⊣ | GLI1 | 16293631 | SIGNOR-276044 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PKA | phosphorylation → down-regulates activity | GLI1 | SIGNOR-276044 |