Entity Details

Name PRKAA1_Thr1074
ID P08151
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
AMPKGLI1Thr1074QRGSSGHtPPPSGPPphosphorylation
down-regulates quantity by destabilization		26190112SIGNOR-253543
PRKAA1GLI1Thr1074QRGSSGHtPPPSGPPphosphorylation
down-regulates activity		26190112SIGNOR-259862
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
AMPKphosphorylation
up-regulates
→
GLI1
PThr1074		phosphorylation
down-regulates
⊣		GLI126190112SIGNOR-253543
PRKAA1phosphorylation
up-regulates
→
GLI1
PThr1074		phosphorylation
down-regulates
⊣		GLI126190112SIGNOR-259862
Regulator Mechanism/Effect Target SIGNOR-ID
AMPKphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		GLI1SIGNOR-253543
PRKAA1phosphorylation
→
down-regulates activity 		GLI1SIGNOR-259862