| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTPRJ | MET | Tyr1365 | NVKCVAPyPSLLSSE | dephosphorylation down-regulates | 12475979 | SIGNOR-96347 |
| PTPRJ | MET | Tyr1365 | NVKCVAPyPSLLSSE | dephosphorylation down-regulates activity | 12475979 | SIGNOR-248703 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTPRJ | dephosphorylation down-regulates ⊣ | MET PTyr1365 | dephosphorylation up-regulates → | MET | 12475979 | SIGNOR-96347 |
| PTPRJ | dephosphorylation down-regulates ⊣ | MET PTyr1365 | dephosphorylation up-regulates → | MET | 12475979 | SIGNOR-248703 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PTPRJ | dephosphorylation down-regulates | MET | SIGNOR-96347 |
| PTPRJ | dephosphorylation → down-regulates activity | MET | SIGNOR-248703 |
