| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTPRB | MET | Tyr1356 | YVHVNATyVNVKCVA | dephosphorylation down-regulates | 21454675 | SIGNOR-173004 |
| PTPRB | MET | Tyr1356 | YVHVNATyVNVKCVA | dephosphorylation down-regulates | 16101282 | SIGNOR-139560 |
| PTPRB | MET | Tyr1356 | YVHVNATyVNVKCVA | dephosphorylation down-regulates activity | 21454675 | SIGNOR-248440 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTPRB | dephosphorylation down-regulates ⊣ | MET PTyr1356 | dephosphorylation up-regulates → | MET | 21454675 | SIGNOR-173004 |
| PTPRB | dephosphorylation down-regulates ⊣ | MET PTyr1356 | dephosphorylation up-regulates → | MET | 16101282 | SIGNOR-139560 |
| PTPRB | dephosphorylation down-regulates ⊣ | MET PTyr1356 | dephosphorylation up-regulates → | MET | 21454675 | SIGNOR-248440 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PTPRB | dephosphorylation![]() down-regulates | MET | SIGNOR-173004 |
| PTPRB | dephosphorylation![]() down-regulates | MET | SIGNOR-139560 |
| PTPRB | dephosphorylation → down-regulates activity | MET | SIGNOR-248440 |