Entity Details

Name ABL1_Tyr686
ID P09619
Role residue
View in

Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
ABL1PDGFRBTyr686IITEYCRyGDLVDYLphosphorylation
up-regulates activity		19275932SIGNOR-276142
ABL2PDGFRBTyr686IITEYCRyGDLVDYLphosphorylation
up-regulates activity		19275932SIGNOR-276140
ABL1PDGFRBTyr686IITEYCRyGDLVDYLphosphorylation
down-regulates		19275932SIGNOR-184552
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
ABL1phosphorylation
up-regulates
→
PDGFRB
PTyr686		phosphorylation
up-regulates
→		PDGFRB19275932SIGNOR-276142
ABL2phosphorylation
up-regulates
→
PDGFRB
PTyr686		phosphorylation
up-regulates
→		PDGFRB19275932SIGNOR-276140
ABL1phosphorylation
up-regulates
→
PDGFRB
PTyr686		phosphorylation
down-regulates
⊣		PDGFRB19275932SIGNOR-184552
Regulator Mechanism/Effect Target SIGNOR-ID
ABL1phosphorylation
→
up-regulates activity 		PDGFRBSIGNOR-276142
ABL2phosphorylation
→
up-regulates activity 		PDGFRBSIGNOR-276140
ABL1phosphorylation
img/direct_inhibition.png
down-regulates 		PDGFRBSIGNOR-184552